Adenosine 3′-phosphate 5′-phosphosulfate lithium salt hydrate
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt hydrate (CAS: 109434-21-1) is a vital biological molecule with the empirical formula C10H15N5O13P2S · xLi+ · yH2O. Its molecular weight is 507.26 (free acid basis). As a key sulfonate donor in vivo, it plays a critical role in sulfation reactions catalysed by sulfotransferases, including the modification of glycans. This compound is also instrumental in researching the function and distribution of biological transporters.
- IUPAC
- 3′-Phosphoadenosine 5′-phosphosulfate lithium salt,APPS,Active sulfate,PAPS
- Synonyms
- 3′-Phosphoadenosine 5′-phosphosulfate lithium salt,APPS,Active sulfate,PAPS

Sulfonation Studies
Serves as a universal sulfonate donor for in vivo sulfonation, crucial for the activity of sulfotransferases in biochemical research.
Glycan Modification Research
Utilised in the study of glycan sulfation, contributing to the understanding of carbohydrate-based biological processes.
Biological Transporter Investigation
Useful for exploring the distribution and functional roles of specific biological transporters within cellular systems.
Metabolic Pathway Research
A key metabolite in understanding sulfate transfer and its impact on various metabolic pathways.
| Molecular weight | 507.26 (free acid basis) |
|---|---|
| Empirical formula | C10H15N5O13P2S · xLi+ · yH2O |
| Assay | ≥60% |
| Storage temperature | −20°C |
| Application | 3′-Phosphoadenosine 5′-phosphosulfate (PAPS) is used as a universal sulfonate donor for in vivo sulfonation by sulfotransferases. PAPS is used for the sulfation of glycans. PAPS is also useful to study the distribution and function of its biological transporter(s). |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Adenosine 3′-phosphate 5′-phosphosulfate lithium salt hydrate used for?
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This compound is used as a universal sulfonate donor for in vivo sulfonation reactions, particularly in the sulfation of glycans. It is also valuable for studying the distribution and function of biological transporters.
What are the CAS number and formula for Adenosine 3′-phosphate 5′-phosphosulfate lithium salt hydrate?
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The CAS number is 109434-21-1, and the empirical formula is C10H15N5O13P2S · xLi+ · yH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥60%. We do not represent this product as USP, BP, EP, or any pharmacopoeial grade.
How should Adenosine 3′-phosphate 5′-phosphosulfate lithium salt hydrate be handled safely?
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This product is a Warning substance and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use with a dust mask (type N95 US), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust.
How is Adenosine 3′-phosphate 5′-phosphosulfate lithium salt hydrate shipped?
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This product is shipped in dry ice.
How can I request a quote or sample?
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Please contact our sales team directly through our website or by phone to request a quotation or a sample.
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