Adenosine 5′-phosphosulfate sodium salt
Adenosine 5′-phosphosulfate sodium salt (CAS: 102029-95-8) is a chemical compound with the formula C10H14N5O10PS and a molecular weight of 427.28 g/mol. This reagent is specifically employed as a substrate for ATP sulfurylase. Its primary application is to facilitate a pyrophosphate-recycling loop, enabling exponential ATP amplification within firefly luciferase ATP luminescence assays and other pyrophosphate regeneration-dependent detection methodologies. It is typically supplied meeting a ~90% assay.
- IUPAC
- APS

ATP Amplification Assays
Adenosine 5′-phosphosulfate sodium salt serves as a key substrate in enzymatic assays. It enables the amplification of ATP signals through the ATP sulfurylase reaction, crucial for luminescence-based detection systems.
Pyrophosphate Regeneration
This compound is instrumental in assays requiring pyrophosphate regeneration. It contributes to a closed-loop system that regenerates pyrophosphate, thereby enhancing the efficiency and sensitivity of the assay.
Luciferase Assays
Utilized in conjunction with firefly luciferase, Adenosine 5′-phosphosulfate sodium salt supports sensitive detection methods by facilitating ATP amplification, a core component of bioluminescence.
| Molecular weight | 427.28 |
|---|---|
| Empirical formula | C10H14N5O10PS |
| Assay | ~90% |
| Storage temperature | −20°C |
| Application | Adenosine 5′ phosphosulfate (APS) is used as a substrate of ATP sulfurylase to complete a PP(i)-recycling loop for exponential ATP amplification in firefly luciferase ATP luminescence assay and other pyrophosphate regeneration-dependent detection assays. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Adenosine 5′-phosphosulfate sodium salt used for?
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Adenosine 5′-phosphosulfate sodium salt is used as a substrate for ATP sulfurylase to complete a PP(i)-recycling loop for exponential ATP amplification in firefly luciferase ATP luminescence assay and other pyrophosphate regeneration-dependent detection assays.
What is the CAS number and chemical formula for Adenosine 5′-phosphosulfate sodium salt?
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The CAS number is 102029-95-8 and the chemical formula is C10H14N5O10PS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Adenosine 5′-phosphosulfate sodium salt with an assay of approximately 90%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Adenosine 5′-phosphosulfate sodium salt be handled safely?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It requires appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Handle in a well-ventilated area.
How is Adenosine 5′-phosphosulfate sodium salt shipped and stored?
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Adenosine 5′-phosphosulfate sodium salt is shipped on dry ice and should be stored at -20°C.
How can I request a quote or sample?
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Please contact our customer service team to request a quote or sample of Adenosine 5′-phosphosulfate sodium salt. Details for contact can be found on our website.
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