(1S,2S)-(−)-1-Phenylpropylene oxide
(1S,2S)-(−)-1-Phenylpropylene oxide (CAS: 4518-66-5) is a chiral epoxide with a molecular weight of 134.18 g/mol. This enantiomerically pure compound serves as a valuable building block in asymmetric synthesis. It is particularly useful for introducing chiral centres into organic molecules, finding applications in the development of complex pharmaceuticals and fine chemicals where precise stereochemistry is critical. Its reactive epoxide ring allows for various transformations.
- IUPAC
- (2S,3S)-(−)-2-Methyl-3-phenyloxirane,trans-(−)-2-Methyl-3-phenyloxirane
- Synonyms
- C9H10O(2S,3S)-(−)-2-Methyl-3-phenyloxiranetrans-(−)-2-Methyl-3-phenyloxirane
Chiral Building Block in Organic Synthesis
Serves as a stereochemically defined precursor for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals where specific enantiomers are required for biological activity.
Asymmetric Synthesis
Utilised in asymmetric reactions to create new chiral centres with high enantioselectivity, facilitating the production of enantiomerically pure target compounds.
Epoxide Chemistry
Undergoes nucleophilic ring-opening reactions, allowing for the controlled introduction of various functional groups while preserving or inverting stereochemistry.
| Molecular weight | 134.18 |
|---|---|
| Empirical formula | C9H10O |
| Assay | 98% |
| Density | 1.003 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.517(lit.) |
| Optical activity | [α]19/D −110°, neat |
| Optical purity | ee: 99% (GLC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 69 °C / 156.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-(−)-1-Phenylpropylene oxide used for?
+
(1S,2S)-(−)-1-Phenylpropylene oxide is primarily used as a chiral building block in asymmetric synthesis for creating enantiomerically pure organic molecules, particularly in pharmaceutical and fine chemical development.
What are the CAS number and molecular formula for (1S,2S)-(−)-1-Phenylpropylene oxide?
+
The CAS number is 4518-66-5, and its empirical formula (Hill notation) is C9H10O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (1S,2S)-(−)-1-Phenylpropylene oxide with an assay of 98% and high optical purity (ee: 99%). TSS does not represent this product as USP, BP, or EP grade.
How should (1S,2S)-(−)-1-Phenylpropylene oxide be handled?
+
Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure good ventilation or use a respirator. Avoid contact with skin, eyes, and clothing. This compound is classified as a Warning with hazards H315, H319, and H335.
Does TSS export (1S,2S)-(−)-1-Phenylpropylene oxide?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (1S,2S)-(−)-1-Phenylpropylene oxide.
How can I request a sample or quote for (1S,2S)-(−)-1-Phenylpropylene oxide?
+
Please contact our sales team or use the online form on our website to request a sample or a detailed quotation.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis