(1S,2S)-2-(Diphenylphosphino)-1,2-diphenylethylamine
(1S,2S)-2-(Diphenylphosphino)-1,2-diphenylethylamine (CAS 1091606-67-5) is a chiral aminophosphine ligand with a molecular weight of 381.45 g/mol. This compound is recognised for its utility in asymmetric synthesis, serving as a key component in the development of stereoselective catalytic processes. Its specific stereochemistry and phosphine functionality make it valuable for applications requiring high enantioselectivity and precise control over chemical transformations.
- Synonyms
- 1091606-67-5C26H24NP

Asymmetric Catalysis
This chiral aminophosphine ligand is employed in asymmetric catalysis to induce enantioselectivity in various chemical reactions. It facilitates the synthesis of chiral molecules, which are critical in pharmaceuticals and fine chemicals.
Chiral Ligand Synthesis
It serves as a building block or catalyst in the synthesis of more complex chiral ligands. These advanced ligands are essential for developing novel catalytic systems for challenging transformations.
Stereoselective Synthesis
The compound's specific stereochemical configuration is leveraged in stereoselective synthesis routes to produce enantiomerically pure or enriched compounds. This is crucial for producing active pharmaceutical ingredients and other stereochemically sensitive molecules.
| Molecular weight | 381.45 |
|---|---|
| Empirical formula | C26H24NP |
| Optical activity | [α]22/D +179°, c = 0.5 in chloroform |
| Melting point | 87-93 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-2-(Diphenylphosphino)-1,2-diphenylethylamine used for?
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(1S,2S)-2-(Diphenylphosphino)-1,2-diphenylethylamine is primarily used as a chiral ligand in asymmetric synthesis and catalysis, enabling the stereoselective production of chiral molecules.
What is the CAS number and formula for (1S,2S)-2-(Diphenylphosphino)-1,2-diphenylethylamine?
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The CAS number is 1091606-67-5 and the empirical formula is C26H24NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated on the certificate of analysis. Please refer to the product's Certificate of Analysis for specific purity information.
How should (1S,2S)-2-(Diphenylphosphino)-1,2-diphenylethylamine be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified as an irritant to the skin, eyes, and respiratory tract (H315, H319, H335).
Is this chemical controlled or scheduled?
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The provided data does not indicate that this chemical is a controlled or scheduled substance.
How is (1S,2S)-2-(Diphenylphosphino)-1,2-diphenylethylamine shipped and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, including (1S,2S)-2-(Diphenylphosphino)-1,2-diphenylethylamine, adhering to all relevant shipping and export regulations.
How can I request a sample or quote?
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To request a sample or a detailed quotation, please contact our sales department through the website or by phone, providing the product name and CAS number.
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