1-Hexadecanethiol
1-Hexadecanethiol (CAS: 2917-26-2, Formula: CH3(CH2)15SH, MW: 258.51) is a long-chain alkyl thiol supplied by Tech Serve Solutions. This compound serves as a key building block in chemical synthesis and materials science. Its primary applications involve the preparation of functionalized nanoparticles and the formation of highly ordered hydrophobic self-assembled monolayers (SAMs) on surfaces, crucial for micro/nanoelectronics and surface modification.
- IUPAC
- Cetyl mercaptan,Hexadecyl mercaptan,Mercaptan C16
- Synonyms
- Cetyl mercaptanHexadecyl mercaptanMercaptan C16

Nanoparticle Functionalization
1-Hexadecanethiol is used to create thiol-functionalized gold nanoparticles. This process involves ligand exchange with existing nanoparticle stabilizers, yielding nanoparticles with precise surface properties for advanced applications.
Self-Assembled Monolayers (SAMs)
This compound forms highly ordered, hydrophobic SAMs due to its long alkane chain. These monolayers are critical in materials science for surface engineering, particularly in micro/nanoelectronics and sensor development.
Chemical Synthesis
As an organic building block, 1-Hexadecanethiol is utilized in various synthetic pathways. Its thiol group allows for diverse chemical transformations, contributing to the creation of complex organic molecules.
| Molecular weight | 258.51 |
|---|---|
| Linear formula | CH3(CH2)15SH |
| Assay | 99% |
| Boiling point | 184-191 °C/7 mmHg(lit.) |
| Density | 0.84 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.462(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 18-20 °C(lit.)20-24 °C |
| Application | Used to prepare thiol-functionalized 1.5 nm gold nanoparticles via a ligand exchange process with triphenylphosphine-stabilized nanoparticles.1 Used in the formation of hydrophobic SAMs. Due to the length of the alkane chain, the resulting monolayer is highly ordered.2 |

Hazard statements
- H319Causes serious eye irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 102 °C / 215.6 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Hexadecanethiol used for?
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1-Hexadecanethiol is primarily used for preparing thiol-functionalized nanoparticles and for forming hydrophobic self-assembled monolayers (SAMs) on surfaces, finding applications in materials science and micro/nanoelectronics.
What are the CAS number and formula for 1-Hexadecanethiol?
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The CAS number for 1-Hexadecanethiol is 2917-26-2, and its linear formula is CH3(CH2)15SH.
What grade and purity does Tech Serve Solutions supply for 1-Hexadecanethiol?
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Tech Serve Solutions supplies 1-Hexadecanethiol with a purity of 99%. This is a technical grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the main safety considerations when handling 1-Hexadecanethiol?
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1-Hexadecanethiol is a Warning substance that causes serious eye irritation (H319) and may cause long lasting harmful effects to aquatic life (H413). Appropriate personal protective equipment, including eyeshields and gloves, should be worn, and handling should be done in a well-ventilated area. Refer to the Safety Data Sheet for full details.
How is 1-Hexadecanethiol packed, shipped, and exported?
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1-Hexadecanethiol is carefully packed to ensure safe transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for 1-Hexadecanethiol?
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To request a sample or a quotation for 1-Hexadecanethiol, please contact our sales team through the website or by phone.
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