(1S,2S)-2-(Diphenylphosphino)cyclohexylamine
(1S,2S)-2-(Diphenylphosphino)cyclohexylamine (CAS: 452304-63-1) is a chiral phosphine ligand with a molecular weight of 283.35. This compound is primarily utilised in asymmetric synthesis, serving as a crucial component in catalytic processes. Its specific stereochemistry makes it valuable for generating enantiomerically enriched products in various chemical transformations, contributing to the efficient production of complex molecules.
- Synonyms
- C18H22NP
Chiral Ligand in Asymmetric Catalysis
This compound functions as a chiral ligand in transition metal-catalysed asymmetric reactions. It facilitates enantioselective transformations, enabling the synthesis of chiral molecules with high optical purity, which are essential in pharmaceutical and fine chemical industries.
Reagent in Organic Synthesis
It is employed as a specialised reagent in complex organic synthesis pathways. Its unique structure allows for specific interactions in catalytic cycles, aiding in the construction of stereodefined carbon frameworks.
Development of Novel Catalytic Systems
Researchers utilise (1S,2S)-2-(Diphenylphosphino)cyclohexylamine in the development and optimisation of new catalytic systems. Its application can lead to more efficient and selective synthetic methodologies.
| Molecular weight | 283.35 |
|---|---|
| Empirical formula | C18H22NP |
| Assay | 97% |
| Optical activity | [α]22/D +103.0°, c = 0.5 in dichloromethane |
| Melting point | 51-56 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2S)-2-(Diphenylphosphino)cyclohexylamine primarily used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis and as a reagent in organic synthesis.
What is the CAS number and formula for (1S,2S)-2-(Diphenylphosphino)cyclohexylamine?
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The CAS number is 452304-63-1 and the empirical formula is C18H22NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 97%. This product is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should (1S,2S)-2-(Diphenylphosphino)cyclohexylamine be handled?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, ensuring good ventilation and avoiding contact with skin, eyes, and clothing. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice.
Is this chemical suitable for food or pharmaceutical applications?
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The provided data does not indicate suitability for food, pharmaceutical, or medicinal applications. It is supplied for research and chemical synthesis purposes.
How is this chemical typically exported or shipped?
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Tech Serve Solutions, as a global supplier and exporter of fine chemicals, ships this product in compliance with international regulations for chemical transport.
How can I request a quote or sample?
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Please contact our sales team directly via the website or email to request a quote or inquire about sample availability.
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