Cetrorelix acetate
Cetrorelix acetate (CAS: 145672-81-7) is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH). It functions as a GnRH antagonist, effectively suppressing the surge of luteinizing hormone (LH) and preventing premature ovulation. This bioactive molecule is primarily utilised in assisted reproductive technologies (ART) to control ovarian stimulation and improve the success rates of fertility treatments. Its precise formulation and high purity make it a valuable research chemical.
- IUPAC
- Cetrotide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide acetic acid salt,NS-75A,SB-75
- Synonyms
- CetrotideN-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide acetic acid saltNS-75ASB-75
Assisted Reproductive Technologies (ART)
Cetrorelix acetate is a key component in controlled ovarian hyperstimulation protocols. It is administered to prevent the premature LH surge, which is critical for optimising egg retrieval in in-vitro fertilisation (IVF) cycles.
Endocrinology Research
As a GnRH antagonist, this compound is used in research settings to study the complex interplay of the hypothalamic-pituitary-gonadal axis. It helps researchers investigate hormone regulation and reproductive physiology.
Hormonal Balance Studies
This molecule serves as a tool for investigating conditions related to hormonal imbalances, particularly those involving the pituitary and gonadal hormones. Its antagonistic action allows for precise manipulation of hormonal feedback loops.
| Molecular weight | 1431.04 (free base basis) |
|---|---|
| Empirical formula | C70H92ClN17O14 · xC2H4O2 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | methanol: soluble10% |
| Storage temperature | −20°C |
Hazard statements
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P281Use personal protective equipment as required
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Risk statements (R) | 60-63 |
| Safety statements (S) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cetrorelix acetate used for?
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Cetrorelix acetate is primarily used in assisted reproductive technologies (ART) to prevent premature luteinizing hormone (LH) surges during controlled ovarian hyperstimulation. It is also utilised in endocrinology research to study hormonal regulation.
What are the CAS number and formula for Cetrorelix acetate?
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The CAS number for Cetrorelix acetate is 145672-81-7. Its empirical formula is C70H92ClN17O14 · xC2H4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cetrorelix acetate with an assay of ≥98% (HPLC). This product is supplied for research and laboratory use, and TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
How should Cetrorelix acetate be handled and stored?
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Cetrorelix acetate is classified under GHS08 with a signal word of 'Warning'. It carries the hazard statement H361 (Suspected of damaging fertility or the unborn child). It should be stored at -20°C. Precautionary statement P281 states to use only with adequate ventilation and avoid breathing dust. Handle with appropriate personal protective equipment.
Is Cetrorelix acetate a controlled substance?
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The provided data does not indicate that Cetrorelix acetate is a controlled substance. However, users should always verify local regulations.
How is Cetrorelix acetate shipped and exported?
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Tech Serve Solutions, as a global supplier and exporter of fine chemicals, can arrange for the shipment and export of Cetrorelix acetate according to international shipping regulations and customer requirements.
How can I request a quote or sample for Cetrorelix acetate?
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To request a quote or a sample of Cetrorelix acetate, please contact our sales team via the website or direct inquiry channels. Provide the product name and CAS number for efficient processing.
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