5-Hydroxy-1-tetralone
5-Hydroxy-1-tetralone (CAS: 28315-93-7), with the molecular formula C10H10O2 and a molecular weight of 162.19 g/mol, is a valuable organic building block. This ketone features a tetralone core functionalised with a hydroxyl group. It serves as a key intermediate in various organic synthesis pathways and has found application in analytical chemistry as an internal standard and fluorescent labelling reagent.
Internal Standard in HPLC
5-Hydroxy-1-tetralone has been employed as an internal standard in High-Performance Liquid Chromatography (HPLC) for the quantitative determination of specific compounds, such as 4-hydroxymephenytoin in human urine samples.
Fluorescent Labeling Reagent
In analytical techniques, it functions as a fluorescent labeling reagent, particularly useful for the microdetection of glycosphingolipids on Thin-Layer Chromatography (TLC) plates.
Synthesis of Benzazepine Derivatives
This compound is utilized in the synthesis of complex organic molecules, including 1,2,3,4-tetrahydro-5H-1-benzazepine-quinone derivatives, contributing to the development of novel chemical structures.
Chiral Molecule Synthesis
It serves as a precursor in the synthesis of new chiral compounds, such as oxathianes, enabling the creation of stereochemically defined molecules for advanced research.
| Molecular weight | 162.19 |
|---|---|
| Empirical formula | C10H10O2 |
| Assay | 99% |
| Application | 5-Hydroxy-1-tetralone was used:• as internal standard during HPLC determination of 4-hydroxymephenytoin (4-OH-M) in human urine1• as fluorescent labeling reagent during microdetection of glycosphingolipid on TLC plates2• in synthesis of 1,2,3,4-tetrahydro-5H-1-benzazepine-quinone derivatives3• in synthesis of new chiral oxathiane4 |
| Melting point | 206-209 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Hydroxy-1-tetralone used for?
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5-Hydroxy-1-tetralone is used as an internal standard in HPLC, a fluorescent labeling reagent, and as a building block in the synthesis of various organic molecules including benzazepine derivatives and chiral oxathianes.
What is the CAS number and molecular formula for 5-Hydroxy-1-tetralone?
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The CAS number for 5-Hydroxy-1-tetralone is 28315-93-7, and its molecular formula is C10H10O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Hydroxy-1-tetralone with an assay of 99%. This product is not supplied as USP, BP, or EP grade.
What are the safety considerations when handling 5-Hydroxy-1-tetralone?
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Handling 5-Hydroxy-1-tetralone requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3.
How is 5-Hydroxy-1-tetralone packed and shipped?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and shipping protocols are followed for all chemicals, including 5-Hydroxy-1-tetralone, adhering to international regulations.
How can I request a quote or sample for 5-Hydroxy-1-tetralone?
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To request a quote or sample for 5-Hydroxy-1-tetralone, please contact our sales team through the website or direct inquiry channels.
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