5-Hydroxy-2(3H)-benzofuranone
5-Hydroxy-2(3H)-benzofuranone (CAS: 2688-48-4; Formula: C8H6O3; Molar Mass: 150.13 g/mol) is a heterocyclic organic compound. This benzofuran derivative serves as a valuable building block in chemical synthesis. It is primarily utilised in research and development settings for the creation of novel molecules and complex organic structures. Its defined chemical properties make it a reliable reagent for various synthetic pathways.
- IUPAC
- 2,5-Dihydroxyphenylacetic acid lactone,Homogentisic lactone
- Synonyms
- 2,5-Dihydroxyphenylacetic acid lactoneHomogentisic lactone

Organic Synthesis Intermediate
Utilised as a key intermediate in multi-step organic synthesis for the construction of more complex molecular architectures. Its reactive sites allow for diverse functional group transformations.
Pharmaceutical Research
A building block employed in medicinal chemistry for the development of potential new drug candidates. It can be incorporated into structures with diverse biological activities.
Fine Chemical Manufacturing
Serves as a precursor in the synthesis of specialized fine chemicals. Its unique structure is beneficial for creating compounds with specific properties.
Heterocyclic Chemistry Studies
A useful reagent for researchers investigating the properties and reactions of benzofuran derivatives and other heterocyclic systems.
| Molecular weight | 150.13 |
|---|---|
| Empirical formula | C8H6O3 |
| Assay | 97% |
| Melting point | 192-194 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Hydroxy-2(3H)-benzofuranone used for?
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5-Hydroxy-2(3H)-benzofuranone (CAS: 2688-48-4) is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and fine chemical manufacturing.
What is the CAS number and formula for 5-Hydroxy-2(3H)-benzofuranone?
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The CAS number is 2688-48-4 and the empirical formula is C8H6O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Hydroxy-2(3H)-benzofuranone with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 5-Hydroxy-2(3H)-benzofuranone be handled?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation.
Is 5-Hydroxy-2(3H)-benzofuranone available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5-Hydroxy-2(3H)-benzofuranone.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quote or sample of 5-Hydroxy-2(3H)-benzofuranone.
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