5-Hydroxy-2-methylpyridine
5-Hydroxy-2-methylpyridine (CAS: 1121-78-4), a pyridine derivative with the formula C6H7NO and a molecular weight of 109.13 g/mol, is a key heterocyclic building block. It is recognised for its utility in chemical synthesis, particularly in the creation of complex organic molecules. This compound serves as a valuable starting material and ligand in various research and development applications within the fine chemical and pharmaceutical sectors.
- IUPAC
- 6-Methyl-3-pyridinol
Synthesis of Pyridine Derivatives
Utilised as a starting reagent for the synthesis of functionalised pyridine aldehydes, such as 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde.
Ligand in Coordination Chemistry
Employed as a ligand in the formation of metal complexes, including a platinum complex with demonstrated protein kinase inhibitory activity at nanomolar concentrations.
Precursor for Ionic Liquids
Forms chiral pyridinium ionic liquids through reaction with chiral reagents like L-menthol chloromethyl ether, enabling applications in chiral separations and catalysis.
Component in Novel Material Synthesis
Incorporated into the synthesis of complex coordination compounds, such as [HNC6H6OH]2[Cu(NC5H5)4(NbOF5)2], for materials research.
| Molecular weight | 109.13 |
|---|---|
| Empirical formula | C6H7NO |
| Assay | 99% |
| Solubility | dichloromethane: soluble |
| Application | • 5-Hydroxy-2-methylpyridine was used as starting reagent for the synthesis of 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde1. • It was used in synthesis of [HNC6H6OH]2[Cu(NC5H5)4(NbOF5)2]2.• It was used as ligand of a platinum complex which showed protein kinase inhibitory action at nanomolar levels3. • It forms a chiral pyridinium ionic liquid on reaction with L-menthol chloromethyl ether4. |
| Melting point | 168-170 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Hydroxy-2-methylpyridine primarily used for?
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5-Hydroxy-2-methylpyridine is primarily used as a starting reagent in organic synthesis for creating functionalised pyridine derivatives and as a ligand in coordination chemistry for developing metal complexes with potential biological activity.
What is the CAS number and formula for 5-Hydroxy-2-methylpyridine?
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The CAS number is 1121-78-4 and the empirical formula is C6H7NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Hydroxy-2-methylpyridine with an assay of 99%. This product is intended for laboratory and research use, and we do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Hydroxy-2-methylpyridine be handled safely?
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5-Hydroxy-2-methylpyridine is classified as Dangerous. Hazards include H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do.
Is 5-Hydroxy-2-methylpyridine a controlled substance?
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The provided data does not indicate that 5-Hydroxy-2-methylpyridine is a controlled substance.
How is this chemical typically packaged and shipped?
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This chemical is typically packaged in containers suitable for fine chemicals and can be exported globally by Tech Serve Solutions.
How can I request a quote or sample of 5-Hydroxy-2-methylpyridine?
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To request a quote or a sample, please use the contact form on the Tech Serve Solutions website or contact our sales team directly.
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