5α-Pregnan-3α-ol-20-one
5α-Pregnan-3α-ol-20-one (CAS: 516-54-1), with the molecular formula C21H34O2 and a molecular weight of 318.49 g/mol, is a naturally occurring neurosteroid. It functions as a positive allosteric modulator of GABA-A receptors. This compound is primarily utilised in scientific research for investigating neurobiological pathways, particularly those involving neurotransmission and ion channel function. Its availability as a high-purity chemical reagent supports advanced studies in cell biology and neuroscience.
- IUPAC
- 3α-Hydroxy-5α-pregnan-20-one,3α-OH-DHP,Allopregnan-3α-ol-20-one,Allopregnanolone
- Synonyms
- 3α-Hydroxy-5α-pregnan-20-one3α-OH-DHPAllopregnan-3α-ol-20-oneAllopregnanolone
Neuroscience Research
5α-Pregnan-3α-ol-20-one serves as a crucial tool in neuroscience for studying the mechanisms of GABAergic neurotransmission. It aids in understanding the role of neurosteroids in modulating neuronal excitability and synaptic function.
Cell Biology Studies
This compound is employed in cell biology research to investigate the impact of neurosteroids on cellular processes and signalling pathways. Its interaction with GABA-A receptors makes it valuable for studies related to cellular responses in neural tissues.
Ion Channel Modulation Research
As a ligand-gated ion channel modulator, 5α-Pregnan-3α-ol-20-one is used to probe the function and regulation of GABA-A receptors. This research contributes to the understanding of neurological disorders associated with ion channel dysfunction.
| Molecular weight | 318.49 |
|---|---|
| Empirical formula | C21H34O2 |
| Form | solid |
| Colour | white |
| Solubility | DMSO: soluble5 mg/mLmethanol: soluble |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5α-Pregnan-3α-ol-20-one used for?
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5α-Pregnan-3α-ol-20-one is primarily used in scientific research for investigating neurobiological pathways, cell signalling, and ion channel function, particularly its role as a GABA-A receptor modulator.
What is the CAS number and molecular formula for 5α-Pregnan-3α-ol-20-one?
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The CAS number is 516-54-1 and the molecular formula is C21H34O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5α-Pregnan-3α-ol-20-one in a research grade. The specific purity will be detailed on the Certificate of Analysis provided with your order. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions when handling 5α-Pregnan-3α-ol-20-one?
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When handling 5α-Pregnan-3α-ol-20-one, appropriate personal protective equipment should be worn, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is also recommended for respiratory protection. Refer to the Safety Data Sheet for detailed handling instructions.
Is 5α-Pregnan-3α-ol-20-one a controlled substance?
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The provided data does not indicate that 5α-Pregnan-3α-ol-20-one is a controlled substance. However, regulations can vary by jurisdiction, and users should verify local import and handling requirements.
How is 5α-Pregnan-3α-ol-20-one packed, shipped, and exported?
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5α-Pregnan-3α-ol-20-one is carefully packed to ensure stability during transit. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to all relevant shipping regulations. Please contact us for specific shipping details.
How can I request a sample or a quote for 5α-Pregnan-3α-ol-20-one?
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To request a sample or a quote, please use the contact form on our website or contact our sales department directly. Provide the product name (5α-Pregnan-3α-ol-20-one) and CAS number (516-54-1) for prompt service.
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