5β-Pregnan-3α-ol-20-one
5β-Pregnan-3α-ol-20-one (CAS: 128-20-1), with the molecular formula C21H34O2 and a molecular weight of 318.49 g/mol, is a steroid compound. It serves as a key intermediate and research chemical within the fields of steroid hormone studies and cell biology. Its specific stereochemistry makes it valuable for investigations into hormonal pathways and biological signalling.
- IUPAC
- 3α-Hydroxy-5β-pregnan-20-one,3α-Hydroxy-5β-tetrahydroprogesterone,Pregnanolone
- Synonyms
- 3α-Hydroxy-5β-pregnan-20-onePregnanolone

Biochemical Research
Utilised in laboratory settings for research into steroid metabolism and hormonal regulation. It can be employed in studies investigating the biological activity of steroid hormones.
Cellular Signaling Studies
Investigates pathways related to cell signaling, particularly those influenced by steroid hormones. Its structure is relevant for understanding receptor interactions and downstream effects.
Endocrinology Research
A tool for researchers studying the endocrine system and the function of steroid hormones within biological systems. It aids in understanding the synthesis and action of endogenous steroids.
| Molecular weight | 318.49 |
|---|---|
| Empirical formula | C21H34O2 |

Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Gabra2(29706) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5β-Pregnan-3α-ol-20-one used for?
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5β-Pregnan-3α-ol-20-one is primarily used in biochemical research, cellular signaling studies, and endocrinology research.
What are the CAS number and formula for 5β-Pregnan-3α-ol-20-one?
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The CAS number is 128-20-1, and the molecular formula is C21H34O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research purposes. Please refer to the product's Certificate of Analysis for specific assay and purity information. We do not represent this product as USP, BP, or EP grade.
How should 5β-Pregnan-3α-ol-20-one be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A respirator with a P3 filter (or equivalent) is recommended. Consult the Safety Data Sheet for detailed guidance.
Is 5β-Pregnan-3α-ol-20-one a controlled substance?
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The provided data does not indicate that 5β-Pregnan-3α-ol-20-one is a controlled substance.
How is 5β-Pregnan-3α-ol-20-one shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, adhering to all necessary regulations for safe and compliant international shipment.
How can I request a sample or quote for 5β-Pregnan-3α-ol-20-one?
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Please contact our sales team directly via the website or provide your details through the 'Request a Quote' or 'Request a Sample' forms.
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