5-Chloro-2-nitroanisole
5-Chloro-2-nitroanisole (CAS: 6627-53-8), with the molecular formula ClC6H3(NO2)OCH3 and a molecular weight of 187.58, is a key organic building block. This nitro compound is widely utilised in chemical synthesis, serving as an intermediate in the development of more complex molecules for various research and industrial applications. Its specific structure makes it valuable for introducing particular functional groups.

Organic Synthesis Intermediate
5-Chloro-2-nitroanisole functions as a versatile intermediate in organic chemistry. It is employed in multi-step syntheses for the preparation of diverse chemical entities and active pharmaceutical ingredients.
Research and Development
This compound is frequently used in R&D settings for exploring new synthetic pathways and developing novel chemical compounds. Its defined structure aids in precise molecular design.
Specialty Chemicals Production
It serves as a precursor in the manufacture of various specialty chemicals. The presence of chloro, nitro, and methoxy groups offers multiple reaction sites for targeted chemical transformations.
| Molecular weight | 187.58 |
|---|---|
| Linear formula | ClC6H3(NO2)OCH3 |
| Assay | 97% |
| Melting point | 70-72 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-nitroanisole used for?
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5-Chloro-2-nitroanisole is primarily used as an intermediate in organic synthesis and for research and development purposes in the chemical and pharmaceutical industries.
What is the CAS number and formula for 5-Chloro-2-nitroanisole?
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The CAS number for 5-Chloro-2-nitroanisole is 6627-53-8, and its molecular formula is ClC6H3(NO2)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloro-2-nitroanisole with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 5-Chloro-2-nitroanisole be handled safely?
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Handle with appropriate personal protective equipment: a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. This compound is classified as an irritant to skin, eyes, and respiratory system.
Does TSS export 5-Chloro-2-nitroanisole?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 5-Chloro-2-nitroanisole.
How can I request a sample or quote for 5-Chloro-2-nitroanisole?
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To request a sample or a quote, please contact our sales team via the website or by phone with your specific requirements.
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