5-Chloro-2-nitroaniline
5-Chloro-2-nitroaniline (CAS: 1635-61-6), with the chemical formula ClC6H3(NO2)NH2 and a molecular weight of 172.57 g/mol, is a critical organic intermediate. This compound functions as a valuable building block in chemical synthesis, particularly in the creation of complex molecules for various downstream applications. Its specific structure makes it useful in the development of pharmaceuticals and other advanced materials.
- IUPAC
- 2-Amino-4-chloro-nitrobenzene

Organic Synthesis Intermediate
5-Chloro-2-nitroaniline serves as a fundamental building block in organic chemistry. It is utilised in the synthesis of more complex nitrogen-containing compounds and heterocyclic structures.
Pharmaceutical Precursor
This chemical has been employed in research and development for the synthesis of potential pharmaceutical agents. Its structure is incorporated into novel molecules designed for therapeutic evaluation.
Material Science Research
The compound may be used in the development of new materials, where its specific functional groups (amine, nitro, and chlorine) contribute to desired material properties.
| Molecular weight | 172.57 |
|---|---|
| Linear formula | ClC6H3(NO2)NH2 |
| Assay | 97% |
| Application | 5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates1. |
| Melting point | 125-129 °C (dec.)(lit.) |



Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
- H373May cause damage to organs through prolonged exposure
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2237 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+,N |
| Risk statements (R) | 26/27/28-33-51/53 |
| Safety statements (S) | 28-36/37-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-nitroaniline used for?
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5-Chloro-2-nitroaniline is primarily used as an intermediate in organic synthesis, including the preparation of potential pharmaceutical agents and other complex organic molecules.
What is the CAS number and chemical formula for 5-Chloro-2-nitroaniline?
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The CAS number is 1635-61-6 and the chemical formula is ClC6H3(NO2)NH2.
What grade and purity does Tech Serve Solutions supply for 5-Chloro-2-nitroaniline?
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Tech Serve Solutions supplies 5-Chloro-2-nitroaniline with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Chloro-2-nitroaniline be handled safely?
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5-Chloro-2-nitroaniline is a toxic substance (Danger: H300, H310, H330) and an environmental hazard (H411). Handle with extreme caution, using full personal protective equipment including eyeshields, face shields, suitable gloves, and appropriate respiratory protection (e.g., type P3 or N100 filters). Ensure work is conducted in a well-ventilated area or fume hood. Avoid release into the environment.
Is 5-Chloro-2-nitroaniline a controlled substance?
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The provided data does not indicate that 5-Chloro-2-nitroaniline is a controlled substance.
How is 5-Chloro-2-nitroaniline packed, shipped, and exported?
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As a specialist global supplier and exporter, Tech Serve Solutions ensures secure and compliant packaging for the safe shipment and export of 5-Chloro-2-nitroaniline worldwide, adhering to all relevant transport regulations.
How can I request a sample or a quote for 5-Chloro-2-nitroaniline?
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To request a sample or a quote, please contact our sales team via the website or directly through the provided contact details. Please reference the product name and CAS number (1635-61-6).
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