Ethyl cyanoformate
Ethyl cyanoformate (CAS: 623-49-4), with the linear formula NCCO₂C₂H₅ and a molecular weight of 99.09 g/mol, is a versatile organic building block. This ester of cyanoformic acid serves as a key intermediate in various chemical syntheses, particularly in the preparation of heterocyclic compounds and other complex organic molecules. Its utility spans across research and development laboratories as well as industrial chemical manufacturing processes.
Organic Synthesis Intermediate
Ethyl cyanoformate is widely employed as a reactive intermediate in organic synthesis. It is particularly useful for the introduction of the cyanoformate group into organic molecules, facilitating the construction of more complex structures.
Heterocyclic Chemistry
This compound is a valuable precursor in the synthesis of various heterocyclic compounds. Its reactivity allows for cyclization reactions, leading to the formation of nitrogen-containing ring systems relevant in medicinal chemistry and materials science.
Reagent in Pharmaceutical Research
In pharmaceutical research, ethyl cyanoformate acts as a building block for the synthesis of active pharmaceutical ingredients (APIs) and their intermediates. It enables the creation of novel molecular architectures for drug discovery.
| Molecular weight | 99.09 |
|---|---|
| Linear formula | NCCO2C2H5 |
| Assay | 99% |
| Boiling point | 115-116 °C(lit.) |
| Density | 1.003 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.381(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 24 °C / 75.2 °F |
| Transport (UN / ADR) | UN 3275 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-23/24/25-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl cyanoformate used for?
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Ethyl cyanoformate (CAS: 623-49-4) is primarily used as a versatile intermediate in organic synthesis, particularly in the preparation of heterocyclic compounds and as a building block in pharmaceutical research.
What are the CAS number and formula for Ethyl cyanoformate?
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The CAS number for Ethyl cyanoformate is 623-49-4 and its linear formula is NCCO₂C₂H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl cyanoformate with a minimum assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated otherwise in the product specifications.
How should Ethyl cyanoformate be handled safely?
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Ethyl cyanoformate is a dangerous substance. It is flammable and toxic if swallowed, in contact with skin, or if inhaled. It causes severe skin burns and eye damage. Always handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.
How is Ethyl cyanoformate packed, shipped, and exported?
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Ethyl cyanoformate is typically packed in compliance with international shipping regulations for hazardous materials. Tech Serve Solutions offers global export services for this chemical.
How can I request a sample or quote for Ethyl cyanoformate?
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To request a sample or a quotation for Ethyl cyanoformate, please contact our sales team through the website or by phone, providing your specific requirements.
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