U-74389G
U-74389G (CAS: 153190-29-5) is a Pregna-1,4,9[11]-triene-3,20-dione derivative with the molecular formula C37H50N6O2 · C4H4O4. This compound is primarily utilised as an antioxidant and cytoprotectant. It has demonstrated efficacy in reducing ethanol-induced gastric mucosal necrosis in animal models and is frequently employed in studies of ischemic injury and hypertension.
- IUPAC
- 21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt
Gastric Mucosal Protection
U-74389G has been shown to significantly mitigate gastric mucosal necrosis induced by ethanol in experimental models, highlighting its cytoprotective properties.
Ischemic Injury Research
The compound is widely applied in animal models to investigate the effects and mechanisms related to ischemic injury, a critical area in cardiovascular and neurological research.
Hypertension Studies
U-74389G serves as a valuable tool in research settings focused on hypertension, aiding in the understanding of associated physiological pathways and potential therapeutic interventions.
| Molecular weight | 726.90 |
|---|---|
| Empirical formula | C37H50N6O2 · C4H4O4 |
| Solubility | ethanol: soluble20 mg/mL, clear, light yellow |
| Storage temperature | −20°C |
| Application | U-74389G has been shown to significantly decrease the level of ethanol-induced gastric mucosal necrosis in portal hypertensive (PHT) rats. Furthermore, U-74389G has been widely used in animal models of ischemic injury and hypertension1. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is U-74389G used for?
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U-74389G is used as an antioxidant and cytoprotectant, particularly in research models of ethanol-induced gastric mucosal necrosis, ischemic injury, and hypertension.
What is the CAS number and formula for U-74389G?
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The CAS number for U-74389G is 153190-29-5 and its formula is C37H50N6O2 · C4H4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies U-74389G typically as a research or technical grade chemical. We do not represent it as USP, BP, or EP grade unless explicitly stated. Purity details are available on the product's Certificate of Analysis.
What are the safety considerations for handling U-74389G?
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Handling U-74389G requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for comprehensive handling and hazard information.
How is U-74389G shipped and exported?
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U-74389G is carefully packaged and exported globally by Tech Serve Solutions, adhering to international shipping regulations for chemical compounds.
How can I request a sample or quote for U-74389G?
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To request a sample or a quotation for U-74389G, please contact our sales department through the website or by phone.
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