4-Phosphonooxy-TEMPO hydrate, free radical
4-Phosphonooxy-TEMPO hydrate (CAS 22690-04-6) is a stable nitroxide radical with a phosphonate ester functional group. It serves as a valuable reagent in organic synthesis, particularly in radical chemistry and oxidation reactions. Its hydrated form offers specific handling and reactivity characteristics, making it a versatile tool for chemists engaged in the development of novel synthetic methodologies and complex molecule construction.
- IUPAC
- 4-Phosphonooxy-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical hydrate
- Synonyms
- 4-Phosphonooxy-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical hydrate

Oxidation Catalysis
This TEMPO derivative can act as a catalyst or co-catalyst in selective oxidation reactions, facilitating the conversion of alcohols to aldehydes and ketones under mild conditions.
Radical Chemistry
As a stable radical, it finds utility in studies and applications involving radical chain mechanisms, polymerization control, and as a spin probe in electron paramagnetic resonance (EPR) spectroscopy.
Organic Synthesis Reagent
Its unique structure allows for its use in a variety of synthetic transformations, contributing to the efficient construction of complex organic molecules and pharmaceutical intermediates.
| Molecular weight | 252.22 (anhydrous basis) |
|---|---|
| Empirical formula | C9H19NO5P · xH2O |
| Storage temperature | 2-8°C |
| Melting point | 270 °C (dec.)(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Phosphonooxy-TEMPO hydrate used for?
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4-Phosphonooxy-TEMPO hydrate is primarily used in chemical synthesis, particularly in radical chemistry and as a reagent for oxidation reactions. It is also employed in the study of stable radicals.
What are the CAS number and formula for 4-Phosphonooxy-TEMPO hydrate?
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The CAS number is 22690-04-6, and its empirical formula is C9H19NO5P · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a technical/research grade material. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Phosphonooxy-TEMPO hydrate be handled?
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This compound is classified as hazardous. It causes serious eye damage and skin irritation. It may also cause respiratory irritation. Always handle with appropriate personal protective equipment in a well-ventilated area.
Is this product suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and this product can be shipped worldwide, subject to applicable regulations.
How can I request a sample or quote?
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Please contact our sales team via the website or direct email to request a sample or a quotation for 4-Phosphonooxy-TEMPO hydrate.
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