Rottlerin

CAS 82-08-6C30H28O8Biochemicals & Reagents

Rottlerin (CAS: 82-08-6), with the molecular formula C30H28O8 and a molecular weight of 516.54, is a natural product and a potent inhibitor of protein kinase C (PKC). It also functions as an inducer of autophagy, making it a valuable tool in cellular signalling and apoptosis research. Rottlerin is primarily utilised in biochemical and cell biology studies to investigate cellular processes and signalling pathways.

IUPAC: 1-[6-[(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one,Mallotoxin

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Rottlerin (C30H28O8) — chemical structure, CAS 82-08-6; Life Science, fine chemical supplied by Tech Serve Solutions

AutophagyAutophagy ActivatorsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand Substrates

01 /Applications

Autophagy Induction

Rottlerin is recognised as an inducer of autophagy, a critical cellular process involved in waste removal and cellular maintenance. It is employed in research to study the mechanisms and consequences of autophagy activation.

Protein Kinase C Inhibition

This compound acts as a selective inhibitor of protein kinase C (PKC), a family of enzymes crucial for signal transduction pathways. Rottlerin is used to delineate the roles of PKC in various cellular functions and disease states.

Cellular Signalling Research

As a bioactive small molecule, Rottlerin serves as a valuable probe in cell biology and signalling research. Its distinct inhibitory profile aids in understanding complex cellular networks and identifying therapeutic targets.

02 /Properties

Molecular weight	516.54
Empirical formula	C30H28O8
Assay	≥85%
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

82-08-6

MDL number

MFCD00017361

PubChem substance

24278679

05 /Additional specifications

Gene Information	human ... CDK2(1017)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Rottlerin used for?

Rottlerin is primarily used in research as an inhibitor of protein kinase C and an inducer of autophagy, aiding studies in cell biology, cellular signalling, and related fields.

What are the CAS number and formula for Rottlerin?

The CAS number for Rottlerin is 82-08-6, and its molecular formula is C30H28O8.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Rottlerin with an assay of ≥85%. This product is intended for research and laboratory use; we do not represent it as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling precautions for Rottlerin?

Rottlerin requires careful handling. Recommended personal protective equipment includes eyeshields, gloves, and an appropriate respirator filter (type N95 or P1). The WGK Germany classification is 3, indicating a high hazard to water.