Roscovitine

CAS 186692-46-6C19H26N6OBiochemicals & Reagents

Roscovitine (CAS 186692-46-6), with the molecular formula C19H26N6O and a molecular weight of 354.45 g/mol, is a potent inhibitor of cyclin-dependent kinases (CDKs). This bioactive small molecule plays a significant role in cell cycle regulation and apoptosis. Its primary applications lie in cancer research and cell biology, serving as a valuable tool for investigating CDK pathways and their involvement in cellular processes and disease.

IUPAC: 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol,6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine
Synonyms: 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol,6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine

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Roscovitine (C19H26N6O) — chemical structure, CAS 186692-46-6; Life Science, fine chemical supplied by Tech Serve Solutions

A to CAntitumor AgentsApoptosis and Cell CycleBioactive Small MoleculesBiochemicals and ReagentsCancer ResearchCell BiologyCell Cycle ProteinsAntibodies and ReagentsCell Cycle Regulators

01 /Applications

Cell Cycle Research

Roscovitine is extensively used to study the role of cyclin-dependent kinases in regulating the cell cycle. It helps researchers understand the mechanisms of cell cycle progression and arrest.

Apoptosis Induction

This compound is employed to investigate its ability to induce apoptosis (programmed cell death) in various cell types. This application is critical in the study of cancer and other diseases involving uncontrolled cell proliferation.

Antitumor Agent Research

As an inhibitor of CDKs, Roscovitine is a subject of research for its potential as an antitumor agent. Its mechanism targets key regulators of cell division in cancerous cells.

Kinase Inhibition Studies

Roscovitine serves as a selective inhibitor for specific CDKs, making it a valuable reagent for biochemical assays and studies focused on kinase signaling pathways.

02 /Properties

Molecular weight	354.45
Empirical formula	C19H26N6O
Assay	≥98% (TLC)
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

186692-46-6

MDL number

MFCD02266401

PubChem substance

24278682

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Roscovitine used for?

Roscovitine is primarily used in scientific research for its role as a cyclin-dependent kinase (CDK) inhibitor. It is applied in studies related to cell cycle regulation, apoptosis induction, and its potential as an antitumor agent.

What are the CAS number and molecular formula for Roscovitine?

The CAS number for Roscovitine is 186692-46-6, and its molecular formula is C19H26N6O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Roscovitine with an assay of ≥98% (TLC). This product is intended for research purposes and is not represented as USP, BP, or EP grade.

What are the safety and handling recommendations for Roscovitine?

For safe handling of Roscovitine, it is recommended to use eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified under WGK Germany 3, indicating a high hazard level.

How is Roscovitine stored and shipped?

Roscovitine should be stored at -20°C. Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and shipping for international delivery.