Ropinirole hydrochloride
Ropinirole hydrochloride (CAS: 91374-20-8), a white to light yellow powder with the molecular formula C16H24N2O · HCl and a molecular weight of 296.84 g/mol, is a non-ergoline dopamine agonist. It functions by selectively stimulating dopamine D2 and D3 receptors in the brain. This compound is primarily utilised in research settings for studies related to neurological disorders, particularly those involving dopaminergic pathways, and as a chemical intermediate in pharmaceutical development.
- IUPAC
- 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride,SKF 101468 hydrochloride
- Synonyms
- 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochlorideSKF 101468 hydrochloride

Dopamine Receptor Research
Ropinirole hydrochloride is used as a tool compound in neuropharmacological research to investigate the role of dopamine D2 and D3 receptors in various physiological and pathological processes. Its selective agonist activity makes it valuable for studying dopaminergic neurotransmission and its modulation.
Pharmaceutical Intermediate
The compound serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its structure and chemical properties are exploited in the development pathways for new therapeutic agents targeting neurological conditions.
Bioactive Small Molecule Studies
As a bioactive small molecule, ropinirole hydrochloride is employed in cell-based assays and biochemical studies to understand cellular signalling pathways and drug discovery mechanisms. Its interaction with GPCRs is of particular interest.
| Molecular weight | 296.84 |
|---|---|
| Empirical formula | C16H24N2O · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | light yellow |
| Solubility | H2O: >10 mg/mL |
| Storage temperature | room temp |


Hazard statements
- H302Harmful if swallowed
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-50/53 |
| Safety statements (S) | 36-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ropinirole hydrochloride used for?
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Ropinirole hydrochloride is primarily used in research for studying dopaminergic pathways and as a chemical intermediate in pharmaceutical development. It acts as a selective dopamine D2 and D3 receptor agonist.
What are the CAS number and formula for Ropinirole hydrochloride?
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The CAS number for Ropinirole hydrochloride is 91374-20-8, and its empirical formula is C16H24N2O · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ropinirole hydrochloride with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Ropinirole hydrochloride be handled safely?
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Handle Ropinirole hydrochloride with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shield, and gloves. It is harmful if swallowed and very toxic to aquatic life, so avoid release to the environment. Ensure adequate ventilation.
How is Ropinirole hydrochloride packaged, shipped, and exported?
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Ropinirole hydrochloride is typically supplied as a light yellow powder and is packaged according to industry standards for safe transport. As a global supplier, Tech Serve Solutions exports this chemical worldwide, adhering to all relevant shipping regulations, including UN 3077.
How can I request a sample or quote for Ropinirole hydrochloride?
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To request a sample or a quote for Ropinirole hydrochloride, please contact our sales team through the website or by phone. Provide your specific requirements, including quantity and intended use.
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