S(+)-Niguldipine hydrochloride
S(+)-Niguldipine hydrochloride (CAS: 113165-32-5) is a chemical compound with the molecular formula C36H39N3O6 · HCl and a molecular weight of 646.17. It presents as a yellow solid. This compound is primarily utilised in research settings as a tool for investigating cellular processes, particularly those involving ion channels and GPCRs. Its specific chemical properties make it valuable in biochemical and cell biology studies.
- IUPAC
- S(+)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(4,4-diphenyl-1-piperidinyl)-propyl methyl ester hydrochloride

Research Tool in Neuroscience
S(+)-Niguldipine hydrochloride serves as a valuable reagent in neuroscience research, aiding in the study of neuronal function and signalling pathways.
Ion Channel Modulation Studies
This compound is employed in the investigation of ion channel activity, contributing to a deeper understanding of their physiological roles.
GPCR Signalling Pathway Research
It is utilised as a modulator in research focused on G protein-coupled receptor (GPCR) signalling pathways, providing insights into cellular communication.
Biochemical Assays
S(+)-Niguldipine hydrochloride finds application in various biochemical assays, supporting the study of biological molecules and their interactions.
| Molecular weight | 646.17 |
|---|---|
| Empirical formula | C36H39N3O6 · HCl |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: soluble13 mg/mLethanol: soluble16 mg/mLmethanol: soluble8 mg/mLH2O: insolubledilute aqueous acid: insoluble |
| Optical activity | [α]22/D +14.62°, c = 0.13 in methanol(lit.) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S(+)-Niguldipine hydrochloride used for?
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S(+)-Niguldipine hydrochloride is primarily used as a research tool in fields such as neuroscience, cell biology, and the study of ion channels and GPCRs. It is not intended for human or animal use.
What is the CAS number and formula for S(+)-Niguldipine hydrochloride?
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The CAS number for S(+)-Niguldipine hydrochloride is 113165-32-5, and its empirical formula is C36H39N3O6 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies S(+)-Niguldipine hydrochloride as a research-grade chemical. The specific assay and purity are detailed in the product specifications; it is not supplied as USP, BP, or EP grade.
How should S(+)-Niguldipine hydrochloride be handled and stored?
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Handle S(+)-Niguldipine hydrochloride with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. Store at -20°C. Dispose of according to local regulations. Refer to the safety data sheet for comprehensive handling information.
Does TSS export S(+)-Niguldipine hydrochloride?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including S(+)-Niguldipine hydrochloride, adhering to all international shipping regulations.
How can I request a sample or quote for S(+)-Niguldipine hydrochloride?
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To request a sample or quote for S(+)-Niguldipine hydrochloride, please contact our sales team through the website or by phone. Specify the CAS number (113165-32-5) in your request.
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