Rubitecan
Rubitecan (CAS: 91421-42-0, C20H15N3O6) is a potent inhibitor of topoisomerase I, a critical enzyme involved in DNA replication and repair. This biochemical compound is widely utilised in scientific research for its ability to disrupt DNA function in cells. Its molecular weight is 393.35 g/mol. Rubitecan serves as a valuable tool in studies investigating cellular mechanisms and exploring potential therapeutic strategies.
- IUPAC
- 9-nitrocamptothecin
- Synonyms
- 9-nitrocamptothecin

Enzyme Inhibition Studies
Rubitecan is employed as a selective inhibitor of topoisomerase I in biochemical and cell biology research. It is used to investigate the role of this enzyme in DNA replication, transcription, and repair pathways.
Cancer Research Tool
As a derivative of camptothecin, Rubitecan is studied for its potential anti-cancer properties. Researchers use it to explore mechanisms of action against cancer cells and to develop new chemotherapeutic agents.
DNA Damage and Repair Research
This compound aids in the study of DNA damage responses and repair mechanisms within cells. By inhibiting topoisomerase I, it allows researchers to observe the consequences of compromised DNA processing.
| Molecular weight | 393.35 |
|---|---|
| Empirical formula | C20H15N3O6 |
| Storage temperature | room temp |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Rubitecan used for?
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Rubitecan is primarily used in research as a topoisomerase I inhibitor to study DNA replication, transcription, repair, and potential anti-cancer mechanisms.
What is the CAS number and formula for Rubitecan?
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The CAS number for Rubitecan is 91421-42-0, and its molecular formula is C20H15N3O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Rubitecan as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeial grade. Purity details are available on the Certificate of Analysis.
How should Rubitecan be handled and stored?
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Handle Rubitecan with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at room temperature. Refer to the Safety Data Sheet for detailed handling and hazard information.
Is Rubitecan a controlled substance?
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The provided data does not indicate that Rubitecan is a controlled substance. Please consult local regulations for specific guidance.
How can I request a sample or quote for Rubitecan?
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To request a sample or quote for Rubitecan, please contact our sales team through the website or by phone, providing your specific requirements.
How is Rubitecan packed and shipped?
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Rubitecan is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations.
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