S(–)-Pindolol
S(–)-Pindolol (CAS: 26328-11-0), with the molecular formula C14H20N2O2 and a molecular weight of 248.32 g/mol, is a white crystalline solid. It functions as a non-selective beta-adrenergic receptor antagonist. This compound is valuable in research settings for studying adrenergic receptor pathways and as a starting point for the synthesis of related pharmaceutical agents. Its optical activity is noted as [α]23/D −4.38°.

Adrenergic Receptor Research
S(–)-Pindolol is utilised in scientific research to investigate the function and modulation of beta-adrenergic receptors (ADRB1) and serotonin receptors (HTR1A, HTR1B). It serves as a tool for understanding cell signaling pathways and neurotransmission.
Pharmaceutical Intermediate
As a bioactive small molecule, this compound can serve as an intermediate in the synthesis of potential therapeutic agents. Its structural features make it a candidate for drug discovery and development programs.
Biochemical Studies
This chemical reagent is employed in biochemical assays and experiments focusing on GPCR modulators and membrane protein interactions. Its specific activity profile is useful for delineating receptor binding and function.
| Molecular weight | 248.32 |
|---|---|
| Empirical formula | C14H20N2O2 |
| Form | solid |
| Colour | white |
| Solubility | 0.1 M NaOH: soluble0.2 mg/mLmethanol: soluble18 mg/mL0.1 M HCl: soluble20 mg/mL45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble3.4 mg/mLH2O: insoluble |
| Optical activity | [α]23/D −4.38°, c = 1% in methanol(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRB1(153), HTR1A(3350), HTR1B(3351) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is S(–)-Pindolol used for?
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S(–)-Pindolol is primarily used in research settings for studying adrenergic receptor pathways, cell signaling, and neurotransmission, and as a biochemical reagent or pharmaceutical intermediate in drug discovery.
What are the CAS number and chemical formula for S(–)-Pindolol?
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The CAS number for S(–)-Pindolol is 26328-11-0, and its chemical formula is C14H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies S(–)-Pindolol as a research-grade chemical. The specific assay and purity are detailed in the product specifications. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling requirements for S(–)-Pindolol?
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Handling S(–)-Pindolol requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK Germany rating of 3, indicating a high hazard to water.
How is S(–)-Pindolol packaged and shipped?
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S(–)-Pindolol is supplied as a solid and is available for export. Packaging details are tailored to ensure product integrity and compliance with shipping regulations.
How can I request a sample or quote for S(–)-Pindolol?
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To request a sample or a quotation for S(–)-Pindolol, please contact the Tech Serve Solutions sales team through our website or direct contact channels.
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