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4-Piperidineethanol

CAS 622-26-4C7H15NOChemical Synthesis

4-Piperidineethanol (CAS: 622-26-4), with the chemical formula C7H15NO and a molecular weight of 129.20 g/mol, is a valuable heterocyclic building block. This compound serves as a key intermediate in the synthesis of various complex organic molecules. Its primary utility lies in its role as a reactant for the development of pharmaceuticals, including potential treatments for malaria and cardiovascular conditions, as well as for creating novel chemical entities.

IUPAC
4-(2-Hydroxyethyl)piperidine
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4-Piperidineethanol (C7H15NO) — chemical structure, CAS 622-26-4; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC5 to C7Chemical SynthesisHeterocyclic Building BlocksPiperidines
01 /Applications

Synthesis of Ursolic Acid Derivatives

4-Piperidineethanol is employed as a reactant in the chemical synthesis of ursolic acid derivatives, contributing to the exploration of new therapeutic agents.

Development of Antimalarial Compounds

This compound serves as a building block for amodiaquine analogues, investigated for the treatment of cerebral malaria, highlighting its pharmaceutical relevance.

Creation of Spiroimidazolidinone NPC1L1 Inhibitors

Used in the synthesis pathway for spiroimidazolidinone compounds that function as NPC1L1 inhibitors, relevant for metabolic research.

Production of Platelet Aggregation Inhibitors

4-Piperidineethanol is a precursor in the synthesis of piperazinyl glutamate pyridines, which are evaluated as orally bioavailable P2Y12 antagonists for inhibiting platelet aggregation.

Neurokinin-2 Receptor Antagonist Synthesis

Its structure lends itself to the development of neurokinin-2 receptor antagonists, contributing to research in various physiological pathways.

Hepatitis C Virus Polymerase Inhibitor Research

This chemical intermediate is utilised in the synthesis of compounds targeting the Hepatitis C virus NS5B polymerase, aiding in the search for antiviral treatments.

02 /Properties
Molecular weight129.20
Empirical formulaC7H15NO
Assay97%
Boiling point131-136 °C/17 mmHg(lit.)
Refractive indexn20/D 1.4902(lit.)
ApplicationReactant for synthesis of:• Ursolic acid derivatives1• Amodiaquine analogues for treatment of cerebral malaria2• Spiroimidazolidinone NPC1L1 inhibitors3• Piperazinyl glutamate pyridines as orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation4• Neurokinin-2 receptor antagonists5• Hepatitis C virus NS5B polymerase inhibitors6
Melting point46-47 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point113 °C / 235.4 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
622-26-4
MDL number
MFCD00006008
PubChem substance
24898559
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Piperidineethanol primarily used for?

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4-Piperidineethanol (CAS: 622-26-4) is primarily used as a reactant and intermediate in the synthesis of various organic molecules, including pharmaceutical agents and complex chemical entities.

What are the CAS number and chemical formula for 4-Piperidineethanol?

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The CAS number for 4-Piperidineethanol is 622-26-4, and its chemical formula is C7H15NO.

What grade and purity does Tech Serve Solutions supply for 4-Piperidineethanol?

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Tech Serve Solutions supplies 4-Piperidineethanol with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated otherwise in the product documentation.

How should 4-Piperidineethanol be handled safely?

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4-Piperidineethanol is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection. Ensure adequate ventilation. Refer to the Safety Data Sheet for detailed handling and emergency procedures.

Is 4-Piperidineethanol a controlled substance?

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The provided data does not indicate that 4-Piperidineethanol (CAS: 622-26-4) is a controlled substance.

How is 4-Piperidineethanol packed, shipped, and exported?

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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations and can be exported worldwide. Specific packaging details are available upon request.

How can I request a sample or a quote for 4-Piperidineethanol?

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To request a sample or a quotation for 4-Piperidineethanol, please contact our sales team through the website or by phone, providing your specific requirements.

Need 4-Piperidineethanol in a specific grade or volume?