4-Piperidinemethanol
4-Piperidinemethanol (CAS 6457-49-4; C6H13NO) is a vital heterocyclic building block with a molecular weight of 115.17 g/mol. This compound serves as a key substrate in solid-phase organic synthesis, particularly for creating secondary amines. Its structure, featuring a piperidine ring with a hydroxymethyl group, makes it a versatile intermediate in chemical synthesis, finding utility across various research and development applications. TSS supplies this reagent at 97% purity.
- IUPAC
- 4-(Hydroxymethyl)piperidine
- Synonyms
- 4-(Hydroxymethyl)piperidine

Solid-Phase Organic Synthesis
4-Piperidinemethanol acts as a crucial substrate in solid-phase organic synthesis methodologies. It is specifically employed in the construction of secondary amines, contributing to the development of complex molecular architectures.
Chemical Synthesis Intermediate
The molecule serves as a versatile intermediate in various chemical synthesis pathways. Its piperidine scaffold and reactive hydroxyl group allow for diverse functionalization, making it valuable in the creation of novel compounds.
Heterocyclic Compound Development
As a heterocyclic building block, 4-Piperidinemethanol is instrumental in the synthesis of more complex heterocyclic structures. These are frequently explored in pharmaceutical and agrochemical research.
| Molecular weight | 115.17 |
|---|---|
| Empirical formula | C6H13NO |
| Assay | 97% |
| Boiling point | 118-120 °C/10 mmHg(lit.) |
| Application | Substrate used in solid-phase organic synthesis of a secondary amine.1 |
| Melting point | 55-59 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3263 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Piperidinemethanol used for?
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4-Piperidinemethanol is primarily used as a substrate in solid-phase organic synthesis for the creation of secondary amines and as a versatile intermediate in general chemical synthesis, particularly for heterocyclic compounds.
What is the CAS number and formula for 4-Piperidinemethanol?
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The CAS number is 6457-49-4 and the empirical formula (Hill notation) is C6H13NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Piperidinemethanol with an assay of 97%. This product is not represented as USP, BP, EP, or pharmaceutical grade.
How should 4-Piperidinemethanol be handled safely?
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4-Piperidinemethanol is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., N100 or P3 filters) must be used. Handle in a well-ventilated area and follow safety statements P280, P305 + P351 + P338, and P310.
Is 4-Piperidinemethanol suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Piperidinemethanol, which is shipped according to international regulations (UN 3263 8 / PGII).
How can I request a sample or quote for 4-Piperidinemethanol?
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Please contact our sales team directly via our website or by phone to request a sample or a quotation for 4-Piperidinemethanol.
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