4-Piperidinopiperidine-1-carbonyl chloride
4-Piperidinopiperidine-1-carbonyl chloride (CAS 103816-19-9, C11H19ClN2O) is a chemical intermediate with a molecular weight of 230.73. This compound serves as a key reactant in the synthesis of various complex organic molecules. Its applications are primarily within research and development settings, contributing to the creation of novel therapeutic agents and chemical entities.
- IUPAC
- 1,4′-Bipiperidinyl-1′-carbonyl chloride,1-Chlorocarbonyl-4-piperidinopiperidine,[1,4′-Bipiperidine]-1′-carbonyl chloride
- Synonyms
- 1,4′-Bipiperidinyl-1′-carbonyl chloride1-Chlorocarbonyl-4-piperidinopiperidine[1,4′-Bipiperidine]-1′-carbonyl chloride
Synthesis of Macrocyclic Ureas
This compound is utilized as a reactant in the synthesis of macrocyclic ureas. These molecules have been investigated for their potential as selective Chk1 inhibitors, relevant in cancer research.
Development of Etoposide Prodrugs
It serves as a building block for etoposide prodrugs designed for dual prodrug-enzyme antitumor therapy. This application highlights its role in advanced pharmaceutical research.
Creation of Phosphodiesterase 4 Inhibitors
4-Piperidinopiperidine-1-carbonyl chloride is employed in the synthetic pathways leading to phosphodiesterase 4 (PDE4) inhibitors, which are targets for various inflammatory and respiratory conditions.
Synthesis of Camptothecin Analogs
The compound is a valuable intermediate for producing analogs of camptothecin, a class of compounds with significant anticancer activity.
| Molecular weight | 230.73 |
|---|---|
| Empirical formula | C11H19ClN2O |
| Application | Reactant for synthesis of:• Macrocyclic ureas as selective Chk1 inhibitors1• Etoposide prodrug for dual prodrug-enzyme antitumor therapy2,3• Phosphodiesterase 4 inhibitors4• Camptothecin analogs5,6 |
| Melting point | 60-64 °C |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Piperidinopiperidine-1-carbonyl chloride used for?
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4-Piperidinopiperidine-1-carbonyl chloride is used as a reactant in the synthesis of various complex organic molecules, including macrocyclic ureas, etoposide prodrugs, phosphodiesterase 4 inhibitors, and camptothecin analogs.
What is the CAS number and formula for 4-Piperidinopiperidine-1-carbonyl chloride?
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The CAS number is 103816-19-9, and the molecular formula is C11H19ClN2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and chemical synthesis purposes. The specific grade and purity should be confirmed with our sales team, as TSS does not represent this product as USP, BP, or EP grade.
How should 4-Piperidinopiperidine-1-carbonyl chloride be handled?
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This compound is classified as Danger with H302 (Harmful if swallowed) and H314 (Causes severe skin burns and eye damage). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is 4-Piperidinopiperidine-1-carbonyl chloride a controlled substance?
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The provided data does not indicate that 4-Piperidinopiperidine-1-carbonyl chloride is a controlled substance.
How is this chemical exported and packed?
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This chemical is shipped internationally according to UN 3261, Hazard Class 8, Packing Group III regulations. Packaging details are available upon request.
How can I request a sample or quote?
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To request a sample or a quote for 4-Piperidinopiperidine-1-carbonyl chloride, please contact the Tech Serve Solutions sales department via our website or direct contact details.
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