(S)-(+)-1,1′-Binaphthyl-2,2′-diyl hydrogenphosphate

CAS 35193-64-7C20H13O4PChemical Synthesis

(S)-(+)-1,1′-Binaphthyl-2,2′-diyl hydrogenphosphate (CAS: 35193-64-7) is a chiral phosphoric acid with the molecular formula C20H13O4P and a molecular weight of 348.29 g/mol. This compound serves as a highly effective chiral Bronsted acid catalyst. It is extensively employed in asymmetric synthesis to promote enantioselective reactions, notably the Mannich reaction, enabling the creation of specific stereoisomers with high optical purity.

IUPAC: (S)-(+)-1,1′-Binaphthalene-2,2′-diyl hydrogen phosphate,(S)-4-Hydroxydinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide
Synonyms: 35193-64-7C20H13O4P(S)-4-Hydroxydinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide

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(S)-(+)-1,1′-Binaphthyl-2,2′-diyl hydrogenphosphate (C20H13O4P) — chemical structure, CAS 35193-64-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsChiral Phosphoric AcidsChiral Resolution Reagents

01 /Applications

Asymmetric Mannich Reaction Catalyst

This chiral phosphoric acid is a valuable catalyst for enantioselective Mannich reactions. It facilitates the stereoselective formation of carbon-carbon bonds, crucial for synthesizing complex chiral molecules.

Chiral Bronsted Acid Catalysis

As a potent chiral Bronsted acid, it catalyses a variety of asymmetric transformations. Its structure allows for effective proton transfer and stereochemical control in organic synthesis.

Synthesis of Chiral Intermediates

Used in the development of chiral building blocks for pharmaceuticals and fine chemicals. Its application ensures the desired enantiomeric excess in the target molecules.

02 /Properties

Molecular weight	348.29
Empirical formula	C20H13O4P
Assay	97%
Optical activity	[α]22/D +595°, c = 1.35 in methanol
Application	Used as a chiral Bronsted acid catalyst in the enantoselective Mannich reaction.1

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

35193-64-7

MDL number

MFCD00010045

PubChem substance

24854963

Beilstein registry

4787775

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-1,1′-Binaphthyl-2,2′-diyl hydrogenphosphate used for?

It is primarily used as a chiral Bronsted acid catalyst in enantioselective reactions, such as the Mannich reaction, for asymmetric synthesis.

What are the CAS number and formula for this compound?

The CAS number is 35193-64-7, and the empirical formula is C20H13O4P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of 97%. It is not represented as USP, BP, EP, or other pharmacopoeial grades.

What are the safety and handling recommendations?

Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK Germany rating of 3.

How is this chemical packed, shipped, and exported?

Tech Serve Solutions expertly packs, handles, and exports fine chemicals globally, adhering to all relevant regulations for safe and compliant transit.