(S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine
(S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine (CAS 23357-52-0) is a chiral amine with the molecular formula C10H13N and a molar mass of 147.22 g/mol. This enantiomerically pure compound serves as a valuable building block in asymmetric synthesis. Its primary applications lie in the development of pharmaceuticals and other complex organic molecules where stereochemistry is critical for efficacy and specificity.
- IUPAC
- (S)-(+)-1-AminoTetralin®,(S)-(+)-1-Aminotetraline
- Synonyms
- (S)-(+)-1-Aminotetraline(S)-(+)-1-AminoTetralin4-Tetrahydro-1-naphthylamine

Chiral Building Block in Pharmaceutical Synthesis
Utilised in the stereoselective synthesis of active pharmaceutical ingredients (APIs) and drug intermediates. Its defined chirality is essential for producing enantiomerically pure target molecules.
Asymmetric Catalysis
Can be employed as a chiral auxiliary or ligand in asymmetric catalysis. This enables the stereocontrolled formation of new chiral centres in organic reactions.
Organic Synthesis Reagent
A versatile intermediate for constructing complex organic molecules. It is particularly useful when the introduction of a chiral amine functionality is required.
| Molecular weight | 147.22 |
|---|---|
| Linear formula | (C10H11)NH2 |
| Assay | ≥98.5% (GC)99% |
| Boiling point | 250 °C |
| Density | 1.010 g/mL at 25 °C |
| Refractive index | n20/D 1.565 |
| Optical purity | enantiomeric excess: ≥98.5% |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C,N |
| Risk statements (R) | 34-51/53 |
| Safety statements (S) | 26-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis, particularly in the pharmaceutical industry for creating enantiomerically pure compounds and as a reagent in asymmetric catalysis.
What is the CAS number and formula for (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine?
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The CAS number is 23357-52-0 and the molecular formula is C10H13N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine with an assay of ≥98.5% (GC) and 99% purity, and an enantiomeric excess of ≥98.5%. We do not represent this product as USP, BP, or EP grade.
How should (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine be handled safely?
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This compound is classified as corrosive (H314) and is harmful if released into the environment. Handle with appropriate personal protective equipment, including gloves, goggles, and a full-face respirator, in a well-ventilated area. Avoid release to the environment.
Is (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine controlled or scheduled?
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The provided data does not indicate that this substance is controlled or scheduled. However, customers should verify local regulations.
How is (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine packed and shipped?
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This chemical is packed and shipped in compliance with UN 2735, Class 8, Packing Group III regulations for corrosive liquids. Tech Serve Solutions is a specialist global supplier and exporter.
How can I request a sample or quote for (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamine?
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To request a sample or obtain a quote, please contact our sales team through the website or by calling our office.
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