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(S)-(+)-1,2-Propanediol

CAS 4254-15-3CH3CH(OH)CH2OHChemical Synthesis

(S)-(+)-1,2-Propanediol (CAS 4254-15-3) is a chiral diol with the molecular formula C3H8O2 and a molecular weight of 76.09 g/mol. This optically active compound, exhibiting a specific rotation of [α]20/D +16.5°, serves as a valuable chiral building block in asymmetric synthesis. Its applications extend to being a substrate for enzyme studies, contributing to its utility in organic synthesis and chemical research.

IUPAC
(S)-(+)-Propylene glycerol
Synonyms
(S)-(+)-Propylene glycerol(S)-Propane-1,2-diol
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(S)-(+)-1,2-Propanediol (CH3CH(OH)CH2OH) — chemical structure, CAS 4254-15-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building BlocksPolyols
01 /Applications

Chiral Synthetic Intermediate

Utilised as a crucial chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules. Its defined stereochemistry is essential for creating enantiomerically pure compounds.

Substrate for Enzyme Studies

Serves as a substrate in biochemical and enzymatic studies, aiding researchers in understanding enzyme mechanisms and kinetics. This application highlights its role in biochemical research.

Organic Synthesis

A versatile reagent in general organic synthesis, particularly where a chiral diol functionality is required. It can be incorporated into various molecular frameworks to introduce chirality.

02 /Properties
Molecular weight76.09
Linear formulaCH3CH(OH)CH2OH
Assay96%
Boiling point186-188 °C/765 mmHg(lit.)
Density1.036 g/mL at 20 °C(lit.)
Refractive indexn20/D 1.432(lit.)
Optical activity[α]20/D +16.5°, neat
Optical purityee: 98% (GLC)
ApplicationChiral synthetic intermediate and substrate for enzyme studies.
03 /Safety & handling
Flash point103 °C / 217 °F
Water hazard class (WGK, DE)1

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
4254-15-3
MDL number
MFCD00004539
PubChem substance
24854270
Beilstein registry
1718871
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-1,2-Propanediol used for?

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(S)-(+)-1,2-Propanediol is used as a chiral synthetic intermediate, a substrate for enzyme studies, and a building block in organic synthesis.

What is the CAS number and formula for (S)-(+)-1,2-Propanediol?

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The CAS number is 4254-15-3 and the linear formula is CH3CH(OH)CH2OH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (S)-(+)-1,2-Propanediol with an assay of 96% and 98% enantiomeric excess (ee). This product is not represented as USP, BP, or EP grade.

How should (S)-(+)-1,2-Propanediol be handled safely?

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The material has a flash point of 103 °C (217 °F). It is classified under WGK Germany 1, indicating a low hazard to water. Standard laboratory precautions should be observed during handling.

How is (S)-(+)-1,2-Propanediol packed and shipped?

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As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and shipping for (S)-(+)-1,2-Propanediol to meet international standards for chemical transport.

How can I request a sample or quote for (S)-(+)-1,2-Propanediol?

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Please contact our sales team via the website or telephone to request a sample or a quotation for (S)-(+)-1,2-Propanediol.

Need (S)-(+)-1,2-Propanediol in a specific grade or volume?