(S)-(+)-1,2-Propanediol
(S)-(+)-1,2-Propanediol (CAS 4254-15-3) is a chiral diol with the molecular formula C3H8O2 and a molecular weight of 76.09 g/mol. This optically active compound, exhibiting a specific rotation of [α]20/D +16.5°, serves as a valuable chiral building block in asymmetric synthesis. Its applications extend to being a substrate for enzyme studies, contributing to its utility in organic synthesis and chemical research.
- IUPAC
- (S)-(+)-Propylene glycerol
- Synonyms
- (S)-(+)-Propylene glycerol(S)-Propane-1,2-diol

Chiral Synthetic Intermediate
Utilised as a crucial chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules. Its defined stereochemistry is essential for creating enantiomerically pure compounds.
Substrate for Enzyme Studies
Serves as a substrate in biochemical and enzymatic studies, aiding researchers in understanding enzyme mechanisms and kinetics. This application highlights its role in biochemical research.
Organic Synthesis
A versatile reagent in general organic synthesis, particularly where a chiral diol functionality is required. It can be incorporated into various molecular frameworks to introduce chirality.
| Molecular weight | 76.09 |
|---|---|
| Linear formula | CH3CH(OH)CH2OH |
| Assay | 96% |
| Boiling point | 186-188 °C/765 mmHg(lit.) |
| Density | 1.036 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.432(lit.) |
| Optical activity | [α]20/D +16.5°, neat |
| Optical purity | ee: 98% (GLC) |
| Application | Chiral synthetic intermediate and substrate for enzyme studies. |
| Flash point | 103 °C / 217 °F |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-1,2-Propanediol used for?
+
(S)-(+)-1,2-Propanediol is used as a chiral synthetic intermediate, a substrate for enzyme studies, and a building block in organic synthesis.
What is the CAS number and formula for (S)-(+)-1,2-Propanediol?
+
The CAS number is 4254-15-3 and the linear formula is CH3CH(OH)CH2OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (S)-(+)-1,2-Propanediol with an assay of 96% and 98% enantiomeric excess (ee). This product is not represented as USP, BP, or EP grade.
How should (S)-(+)-1,2-Propanediol be handled safely?
+
The material has a flash point of 103 °C (217 °F). It is classified under WGK Germany 1, indicating a low hazard to water. Standard laboratory precautions should be observed during handling.
How is (S)-(+)-1,2-Propanediol packed and shipped?
+
As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and shipping for (S)-(+)-1,2-Propanediol to meet international standards for chemical transport.
How can I request a sample or quote for (S)-(+)-1,2-Propanediol?
+
Please contact our sales team via the website or telephone to request a sample or a quotation for (S)-(+)-1,2-Propanediol.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis