(S)-(+)-1,2-Isopropylideneglycerol

CAS 22323-82-6C6H12O3Chemical Synthesis

(S)-(+)-1,2-Isopropylideneglycerol (CAS 22323-82-6), a chiral building block with the molecular formula C6H12O3 and a molecular weight of 132.16 g/mol, is supplied by TSS at 98% purity. This optically active compound, exhibiting a specific rotation of [α]20/D +13.5°, is primarily utilised in organic synthesis, particularly in asymmetric reactions. Its defined stereochemistry makes it a valuable precursor for constructing complex chiral molecules.

IUPAC: (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol,1,2-Isopropylidene-sn-glycerol,D-α,β-Isopropylideneglycerol,D-(+)-Solketal,D-1,2-O-isopropylidene-sn-glycerol
Synonyms: (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol1,2-Isopropylidene-sn-glycerolD-α,β-IsopropylideneglycerolD-(+)-SolketalD-1,2-O-isopropylidene-sn-glycerol

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(S)-(+)-1,2-Isopropylideneglycerol (C6H12O3) — chemical structure, CAS 22323-82-6; Chemistry, fine chemical supplied by Tech Serve Solutions

AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Chiral Synthesis Intermediate

Serves as a crucial chiral building block in the synthesis of complex organic molecules. Its defined stereochemistry is essential for creating enantiomerically pure compounds.

Asymmetric Synthesis

Employed in asymmetric synthesis routes, enabling the stereoselective formation of new chiral centres. It facilitates the production of optically active pharmaceuticals and fine chemicals.

Synthesis of Triols

Used in specific synthetic pathways, such as the preparation of chiral allylic triols via SO2 extrusion from α,β-epoxysulfones, demonstrating its utility in specialised organic transformations.

02 /Properties

Molecular weight	132.16
Empirical formula	C6H12O3
Assay	98%
Boiling point	82-83 °C/14 mmHg(lit.)
Density	1.07 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.434(lit.)
Optical activity	[α]20/D +13.5°, neat
Optical purity	ee: 99% (GLC)
Storage temperature	2-8°C
Application	Used in a synthesis of a chiral allylic triol via extrusion of SO2 from an α,β-epoxysulfone.1

03 /Safety & handling

Protective equipment	Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	90 °C / 194 °F
Transport (UN / ADR)	NA 1993 / PGIII
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

22323-82-6

MDL number

MFCD00063239

PubChem substance

24854267

Beilstein registry

80118

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-1,2-Isopropylideneglycerol used for?

(S)-(+)-1,2-Isopropylideneglycerol is used as a chiral building block in organic synthesis, particularly in asymmetric synthesis and for preparing chiral allylic triols.

What is the CAS number and molecular formula for (S)-(+)-1,2-Isopropylideneglycerol?

The CAS number is 22323-82-6 and the empirical formula is C6H12O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-(+)-1,2-Isopropylideneglycerol with an assay of 98%. This is a technical/research grade product, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling considerations for (S)-(+)-1,2-Isopropylideneglycerol?

This compound has a flash point of 90°C (194°F) and is classified under WGK Germany 3. Appropriate personal protective equipment, including eyeshields and chemical-resistant gloves, should be used. Refer to the safety data sheet for full handling information.

How is (S)-(+)-1,2-Isopropylideneglycerol typically shipped and exported?

As per the provided data, it is classified as NA 1993 / PGIII for transport. TSS is experienced in global export and can provide details on shipping and packaging for international destinations.

How can I request a sample or a quote for (S)-(+)-1,2-Isopropylideneglycerol?

To request a sample or obtain a quote, please contact our sales team via the website or direct email, providing your contact details and the quantity required.