Dichloroacetic acid
Dichloroacetic acid (CAS 79-43-6), with the linear formula Cl2CHCOOH and a molecular weight of 128.94 g/mol, is a strong organic acid. It is recognised for its utility as a chemical intermediate and reagent in various synthetic processes. Its applications span research and development, particularly in fields investigating cellular metabolism and cancer research, where it functions as an inhibitor of aerobic glycolysis. Tech Serve Solutions offers this compound at a high purity level.
- Synonyms
- 2,2-Dichloroacetic acidDichloroacetic acidDichlorine acid
Chemical Synthesis Intermediate
Dichloroacetic acid serves as a valuable building block in organic synthesis. Its reactive nature allows for its incorporation into more complex molecules, contributing to the development of novel compounds in research settings.
Research in Cellular Metabolism
This acid is widely employed in biochemical research to study cellular respiration and energy production pathways. It acts as an inhibitor of enzymes like pyruvate dehydrogenase kinase (PDK), impacting aerobic glycolysis, also known as the Warburg effect.
Cancer Research Applications
Due to its influence on metabolic pathways, dichloroacetic acid is a subject of investigation in cancer research. Its ability to modulate cellular energy metabolism makes it a tool for exploring new therapeutic strategies.
Analytical Reagent
Dichloroacetic acid is suitable for use as an analytical standard, including for methods such as those specified by the US EPA. Its defined purity ensures reliable results in quantitative analyses.
| Molecular weight | 128.94 |
|---|---|
| Linear formula | Cl2CHCOOH |
| Assay | ≥99% |
| Grade | ReagentPlus® |
| Boiling point | 194 °C(lit.) |
| Density | 1.563 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.466(lit.) |
| Melting point | 9-11 °C(lit.) |
| Concentration | 3% in methylene chloride |
| Vapour pressure | 0.19 mmHg (20 °C) |
| Vapour density | 4.5 (vs air) |
| Storage temperature | 2-8°C |
| Impurities tested | ≤0.01% water |
| Suitability | suitable for 552.2 per US EPA |
Hazard statements
- H314Causes severe skin burns and eye damage
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 1764 8 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C,N |
| Risk statements (R) | 35-50 |
| Safety statements (S) | 26-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ALDH1A1(216), PDK1(5163)rat ... Pdk1(116551) |
|---|---|
| Feature | standard type calibration |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dichloroacetic acid used for?
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Dichloroacetic acid is primarily used as a chemical intermediate in synthesis, a reagent in research studying cellular metabolism and cancer, and as an analytical standard.
What is the CAS number and chemical formula for Dichloroacetic acid?
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The CAS number is 79-43-6, and its linear formula is Cl2CHCOOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dichloroacetic acid at a ReagentPlus® grade with an assay of ≥99%. TSS does not represent this product as USP, BP, or EP grade.
How should Dichloroacetic acid be handled safely?
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Dichloroacetic acid is corrosive and harmful to aquatic life. Handle with appropriate personal protective equipment, including gloves, goggles, and a suitable respirator, and avoid release into the environment. Refer to the Safety Data Sheet for detailed handling instructions.
How is Dichloroacetic acid packed, shipped, and exported?
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Dichloroacetic acid is typically packed in appropriate containers for chemical transport and is exported globally by Tech Serve Solutions. Specific shipping and export details can be provided upon request.
How can I request a sample or quote for Dichloroacetic acid?
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To request a sample or a quote for Dichloroacetic acid, please contact our sales team through the website or by phone, providing your specific requirements.
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