(S)-(+)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a;3,4-a′]dinaphthalen-4-yl)morpholine
(S)-(+)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a;3,4-a′]dinaphthalen-4-yl)morpholine (CAS: 1044553-58-3), with the molecular formula C24H20NO3P and a molecular weight of 401.39 g/mol, is a highly effective chiral phosphoramidite ligand. It is a key component in asymmetric synthesis, particularly recognised for its role in catalysing stereoselective reactions. This compound is part of the DSM MonoPhos family, known for their privileged structures that facilitate high efficiency in chemical transformations.
- Synonyms
- (S)-(+)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a3,4-a′]dinaphthalen-4-yl)morpholine4-(3,5-Dioxa-4-phosphacyclohepta[2,1-a3,4-a′]dinaphthalen-4-yl)morpholine
![(S)-(+)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a;3,4-a′]dinaphthalen-4-yl)morpholine — chemical structure, CAS 1044553-58-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1044553-58-3.png&w=3840&q=75)
Asymmetric Catalysis
This phosphoramidite ligand is extensively utilised in asymmetric catalysis to induce high enantioselectivity in a variety of chemical transformations. Its chiral nature makes it invaluable for synthesising enantiomerically pure compounds.
Pharmaceutical Intermediate Synthesis
The ability to control stereochemistry is crucial in pharmaceutical development. This compound aids in the synthesis of chiral drug intermediates, ensuring the production of specific enantiomers required for therapeutic efficacy.
Fine Chemical Production
It serves as a critical reagent in the fine chemical industry for producing complex molecules with defined stereocentres, contributing to the development of advanced materials and specialty chemicals.
Ligand for Transition Metal Catalysis
As a privileged ligand, it forms active catalytic complexes with transition metals, enabling a broad scope of challenging organic reactions with improved yields and selectivities.
| Molecular weight | 401.39 |
|---|---|
| Empirical formula | C24H20NO3P |
| Assay | 97% |
| Application | DSM MonoPhos Family of Highly Efficient Privileged Ligands |
| Melting point | 233-239 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a;3,4-a′]dinaphthalen-4-yl)morpholine used for?
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This compound is primarily used as a chiral phosphoramidite ligand in asymmetric synthesis, particularly within the DSM MonoPhos family, for catalysing stereoselective organic reactions.
What is the CAS number and molecular formula for this compound?
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The CAS number is 1044553-58-3, and the molecular formula is C24H20NO3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 3, indicating a high hazard to water.
How is this chemical typically shipped or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, equipped to handle international shipments of this product according to all regulatory requirements.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please contact our sales team through the official Tech Serve Solutions website or your dedicated account manager.
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