(S)-(+)-1,1′-Bi-2-naphthol bis(trifluoromethanesulfonate)

CAS 128544-05-8(CF3SO3C10H6-)2Chemical Synthesis

(S)-(+)-1,1′-Bi-2-naphthol bis(trifluoromethanesulfonate) (CAS: 128544-05-8) is a key chiral intermediate with a molecular weight of 550.45. This compound is instrumental in asymmetric synthesis, particularly in the preparation of advanced chiral phosphine ligands. Its unique stereochemistry makes it valuable for developing enantioselective catalytic processes across various chemical sectors. TSS supplies this high-purity reagent for research and industrial applications.

IUPAC: (S)-1,1′-Bi(2-naphthol) bis(trifluoromethanesulfonate),(S)-1,1′-Binaphthalene-2,2′-diyl bis(trifluoromethanesulfonate)
Synonyms: (S)-1,1′-Bi(2-naphthol) bis(trifluoromethanesulfonate)(S)-1,1′-Binaphthalene-2,2′-diyl bis(trifluoromethanesulfonate)

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(S)-(+)-1,1′-Bi-2-naphthol bis(trifluoromethanesulfonate) ((CF3SO3C10H6-)2) — chemical structure, CAS 128544-05-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisBINOLsChemical SynthesisChiral CatalystsLigandsand Reagents

01 /Applications

Chiral Ligand Synthesis

Serves as a crucial precursor for the synthesis of chiral phosphine ligands. These ligands are essential for catalysing enantioselective reactions, enabling the production of single-enantiomer pharmaceuticals and fine chemicals.

Asymmetric Catalysis

This compound's derivatives are employed as privileged ligands in asymmetric catalysis. They facilitate highly selective transformations, crucial for producing chiral molecules with specific stereochemistry.

Organic Synthesis Intermediate

A versatile building block in organic synthesis, enabling the construction of complex chiral molecules. Its triflate groups are excellent leaving groups, facilitating further functionalisation.

02 /Properties

Molecular weight	550.45
Linear formula	(CF3SO3C10H6-)2
Assay	97%
Optical activity	[α]21/D +148°, c = 1 in chloroform
Application	Used as an intermediate in the preparation of chiral phosphine ligands1 for asymmetric synthesis.2
Melting point	83-85 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

128544-05-8

MDL number

MFCD00274615

Beilstein registry

3579131

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(+)-1,1′-Bi-2-naphthol bis(trifluoromethanesulfonate) used for?

It is primarily used as an intermediate in the preparation of chiral phosphine ligands for asymmetric synthesis.

What is the CAS number and formula for (S)-(+)-1,1′-Bi-2-naphthol bis(trifluoromethanesulfonate)?

The CAS number is 128544-05-8 and the linear formula is (CF3SO3C10H6-)2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of 97%. TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the specifications.

How should (S)-(+)-1,1′-Bi-2-naphthol bis(trifluoromethanesulfonate) be handled safely?

This compound is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a suitable respirator. Refer to the safety data sheet for full details.

How is this chemical shipped and exported?

This product is classified under UN 3261, Hazard Class 8, Packing Group II, indicating it is a corrosive solid, acidic, organic, n.o.s. TSS ensures compliant packaging and documentation for global export.