(S)-(+)-2-Phenylglycine methyl ester hydrochloride
(S)-(+)-2-Phenylglycine methyl ester hydrochloride (CAS: 15028-39-4) is a chiral building block with the molecular formula C6H5CH(NH2)CO2CH3·HCl and a molecular weight of 201.65 g/mol. This compound is primarily utilised in chemical synthesis and peptide chemistry. Its specific stereochemistry makes it a valuable precursor in the creation of complex molecules where chirality is essential, particularly in the development of pharmaceutical intermediates and other fine chemicals.

Chiral Synthesis
Serves as a key chiral intermediate in asymmetric synthesis, enabling the stereoselective construction of complex organic molecules.
Peptide Chemistry
Incorporated into peptide synthesis as an unnatural amino acid derivative to modify peptide structure and function.
Pharmaceutical Intermediates
Used in the development pathway for various active pharmaceutical ingredients (APIs) requiring precise stereochemical control.
Chemical Biology Research
Employed in research settings to explore new molecular entities and biochemical pathways involving chiral amino acid derivatives.
| Molecular weight | 201.65 |
|---|---|
| Linear formula | C6H5CH(NH2)CO2CH3·HCl |
| Assay | 97% |
| Optical activity | [α]20/D +120°, c = 1 in H2O |
| Melting point | 200 °C (dec.)(lit.) |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-2-Phenylglycine methyl ester hydrochloride used for?
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(S)-(+)-2-Phenylglycine methyl ester hydrochloride is used as a chiral building block in chemical synthesis, particularly in peptide chemistry and for the development of pharmaceutical intermediates.
What is the CAS number and formula?
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The CAS number is 15028-39-4 and the linear formula is C6H5CH(NH2)CO2CH3·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. This is a technical or research grade product, and we do not represent it as USP, BP, or EP grade.
What are the safety considerations for handling this chemical?
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This compound is classified as a Warning (GHS07) and causes serious eye irritation (H319). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Avoid contact with eyes and ensure adequate ventilation.
Can TSS export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team via the website or phone to request a sample or a formal quotation.
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