GNF-2
GNF-2 (CAS: 778270-11-4), a synthetic organic compound with the molecular formula C18H13F3N4O2 and a molecular weight of 374.32 g/mol, is supplied by TSS as an off-white solid. This molecule is recognised for its role in biochemical research, particularly as an apoptosis inhibitor. Its primary applications lie in scientific investigations exploring cell death pathways, kinase inhibition, and related cellular processes, making it a valuable reagent for biological and pharmaceutical research.
- IUPAC
- 3-[6-[[4-(Trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]benzamide
Apoptosis Research
GNF-2 acts as an inhibitor of apoptosis, making it a valuable tool for researchers studying programmed cell death mechanisms and pathways. Its use can help elucidate the complex signaling cascades involved in cellular survival and demise.
Kinase Inhibition Studies
This compound is employed in research focused on kinase and phosphatase biology, specifically targeting non-receptor tyrosine kinases like c-Abl. It aids in understanding the role of these enzymes in cellular signaling and disease.
Cell Biology Investigations
GNF-2 serves as a bioactive small molecule for exploring cellular processes. Its application extends to studies involving cell cycle regulation and cell signaling, particularly within neuroscience research contexts.
| Molecular weight | 374.32 |
|---|---|
| Empirical formula | C18H13F3N4O2 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | off-white |
| Solubility | H2O: DMSO: ≥5 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GNF-2 used for?
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GNF-2 is primarily used in scientific research as an apoptosis inhibitor and for studies involving kinase and phosphatase biology, particularly non-receptor tyrosine kinases such as c-Abl. It aids in investigating cell death pathways, cell cycle regulation, and cellular signaling.
What are the CAS number and molecular formula for GNF-2?
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The CAS number for GNF-2 is 778270-11-4, and its molecular formula is C18H13F3N4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies GNF-2 with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should GNF-2 be handled and stored?
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GNF-2 is a warning compound (GHS07) that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Store at 2-8°C.
Is GNF-2 a controlled substance?
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The provided data does not indicate that GNF-2 is a controlled substance.
How is GNF-2 packed and exported?
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GNF-2 is supplied as an off-white solid. TSS is a specialist global supplier and exporter of fine chemicals, ensuring appropriate packaging for safe transit.
How can I request a quote or sample for GNF-2?
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To request a quote or sample for GNF-2, please contact the Tech Serve Solutions sales team directly through our website or provided contact details.
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