GNF-5
GNF-5 (CAS: 778277-15-9, C20H17F3N4O3) is a chemical compound with a molecular weight of 418.37 g/mol. It is supplied as a white to beige powder with an assay of ≥98% purity. GNF-5 is primarily utilized in research settings for its role in cell biology, particularly within cell signaling and neuroscience, and as an inhibitor in kinase/phosphatase and non-receptor tyrosine kinase pathways, including c-Abl.
- IUPAC
- N-(2-Hydroxyethyl)-3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide

Kinase/Phosphatase Biology Research
GNF-5 serves as a valuable tool for researchers investigating kinase and phosphatase signalling pathways. Its inhibitory properties make it useful for studying the roles of these enzymes in cellular processes.
Non-Receptor Tyrosine Kinase Studies
This compound is employed in research focused on non-receptor tyrosine kinases, such as c-Abl. It aids in elucidating the functions and regulatory mechanisms of these critical enzymes in cell biology.
Cell Signaling and Neuroscience
GNF-5 is utilized in studies related to cell signaling and neuroscience, contributing to a deeper understanding of neuronal function and the complex molecular events within the nervous system.
| Molecular weight | 418.37 |
|---|---|
| Empirical formula | C20H17F3N4O3 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble10 mg/mL (clear solution) |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36 |
| Safety statements (S) | 22-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GNF-5 used for?
+
GNF-5 is used in scientific research, primarily within cell biology, cell signaling, neuroscience, and as an inhibitor for kinase/phosphatase and non-receptor tyrosine kinase pathways, including c-Abl.
What is the CAS number and formula for GNF-5?
+
The CAS number for GNF-5 is 778277-15-9, and its molecular formula is C20H17F3N4O3.
What grade and purity does Tech Serve Solutions supply for GNF-5?
+
Tech Serve Solutions supplies GNF-5 with an assay of ≥98% purity by HPLC. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should GNF-5 be handled safely?
+
GNF-5 is classified as Danger with hazard statements H301 (Toxic if swallowed) and H319 (Causes serious eye irritation). Handle with appropriate personal protective equipment, avoid ingestion and eye contact. Refer to the Safety Data Sheet for full handling instructions.
How is GNF-5 packed and shipped by TSS?
+
GNF-5 is supplied as a powder and is stored at 2-8°C. It is shipped internationally under UN 2811, Hazard Class 6.1, Packing Group III regulations.
How can I request a quote or sample of GNF-5?
+
To request a quote or a sample of GNF-5, please contact our sales team via the website or directly by phone. We are happy to assist with your research needs.
▶ Related products

(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology

(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis