GF 109203X

CAS 133052-90-1C25H24N4O2Cell Biology

GF 109203X (CAS: 133052-90-1), a synthetic compound with the molecular formula C25H24N4O2 and a molecular weight of 412.48 g/mol, is a potent inhibitor of protein kinase C. It is widely utilised in biological research for its ability to modulate cell signalling pathways. This compound serves as a valuable tool in studies investigating cellular processes such as autophagy and cell proliferation.

IUPAC: 3-(N-[Dimethylamino]propyl-3-indolyl)-4-(3-indolyl)maleimide,3-[1-[3-(Dimethylamino)propyl]1H-indol-3-yl]-4-(1Hindol-3-yl)1H-pyrrole-2,5dione,Bisindolylmaleimide I
Synonyms: Bisindolylmaleimide I3-(N-[Dimethylamino]propyl-3-indolyl)-4-(3-indolyl)maleimide3-[1-[3-(Dimethylamino)propyl]1H-indol-3-yl]-4-(1Hindol-3-yl)1H-pyrrole-2,5dione

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GF 109203X (C25H24N4O2) — chemical structure, CAS 133052-90-1; Life Science, fine chemical supplied by Tech Serve Solutions

AutophagyAutophagy ActivatorsCell BiologyKinase/Phosphatase Biology

01 /Applications

Autophagy Research

GF 109203X acts as an autophagy activator, making it instrumental in studying the complex mechanisms of cellular self-degradation and its implications in various physiological and pathological conditions.

Cell Biology Investigations

This compound is employed in cell biology to investigate the roles of protein kinases in cellular functions, including growth, differentiation, and survival. Its selective inhibition aids in dissecting signalling cascades.

Neuroscience Studies

As a modulator of cell signaling, GF 109203X finds application in neuroscience research, particularly in understanding pathways relevant to neuronal function and potential therapeutic targets.

Kinase/Phosphatase Pathway Analysis

Researchers utilise GF 109203X to probe the intricacies of kinase and phosphatase biology, aiding in the characterisation of these critical enzyme families and their regulatory networks.

02 /Properties

Molecular weight	412.48
Empirical formula	C25H24N4O2
Assay	≥90% (HPLC)
Solubility	DMSO: soluble (~1 mg/ml)
Storage temperature	2-8°C
Biological source	synthetic

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H302Harmful if swallowed
H351Suspected of causing cancer

Precautionary statements

P281Use personal protective equipment as required

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-40
Safety statements (S)	36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

133052-90-1

MDL number

MFCD00236428

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is GF 109203X used for?

GF 109203X is used in scientific research as a protein kinase inhibitor, primarily to study autophagy, cell signalling, and related biological processes.

What are the CAS number and formula for GF 109203X?

The CAS number for GF 109203X is 133052-90-1, and its empirical formula is C25H24N4O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies GF 109203X with an assay of ≥90% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should GF 109203X be handled and stored?

GF 109203X is classified with GHS07 and GHS08 symbols and carries a Warning signal word. It is harmful if swallowed (H302) and suspected of causing cancer (H351). Handle with appropriate personal protective equipment and store at 2-8°C.