4-Propoxyaniline
4-Propoxyaniline (CAS: 4469-80-1), with the chemical formula C9H13NO, is an organic compound with a molecular weight of 151.21 g/mol. This aromatic amine, featuring a propoxy group attached to the aniline ring, serves as a valuable building block in organic synthesis. It is primarily utilised as a reactant in the preparation of specific chemical compounds, contributing to the development of novel molecules within research and development settings.
- IUPAC
- 4-Propoxyphenylamine,p-Propoxyaniline
- Synonyms
- 4-Propoxyphenylaminep-Propoxyaniline

Preparation of Aggrecanase Inhibitors
4-Propoxyaniline acts as a key reactant in the synthetic pathways for developing aggrecanase inhibitors. These compounds are of interest for their potential therapeutic applications in managing conditions related to cartilage degradation.
Organic Synthesis Intermediate
As a functionalised aniline derivative, 4-Propoxyaniline is employed as a versatile intermediate in various organic synthesis processes. Its structure allows for diverse chemical transformations, making it useful in the creation of complex organic molecules.
Building Block for Novel Compounds
This chemical serves as a fundamental building block, enabling chemists to construct more elaborate molecular architectures. Its reactivity profile makes it suitable for incorporation into diverse research projects exploring new chemical entities.
| Molecular weight | 151.21 |
|---|---|
| Linear formula | CH3CH2CH2OC6H4NH2 |
| Application | Reactant for:• Preparation of aggrecanase inhibitors1 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Propoxyaniline used for?
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4-Propoxyaniline is used as a reactant in the preparation of aggrecanase inhibitors and as a versatile building block in organic synthesis for creating novel compounds.
What is the CAS number and chemical formula for 4-Propoxyaniline?
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The CAS number for 4-Propoxyaniline is 4469-80-1, and its chemical formula is C9H13NO (linear formula: CH3CH2CH2OC6H4NH2).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Propoxyaniline. The specific grade and purity are available upon request, and it is not represented as USP, BP, or EP grade.
How should 4-Propoxyaniline be handled safely?
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4-Propoxyaniline is a warning hazardous substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields and gloves, and handle in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
How is 4-Propoxyaniline shipped and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, professionally packs and ships chemicals worldwide, adhering to all relevant transportation and export regulations.
How can I request a sample or quote for 4-Propoxyaniline?
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To request a sample or a quote for 4-Propoxyaniline, please contact the TSS sales team through the website or by phone, providing your specific requirements.
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