UCL 2077

CAS 918311-87-2C25H22N2Cell Biology

UCL 2077 (CAS: 918311-87-2, C25H22N2) is a white solid chemical compound with a molecular weight of 350.46. It is primarily utilized in research settings for its role in modulating ion channel activity. Specifically, UCL 2077 has been employed in studies investigating slow afterhyperpolarization in neurons and its effects on neuronal excitability in brain regions like the hippocampus.

IUPAC: (3-Triphenylmethylaminomethyl)pyridine

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UCL 2077 (C25H22N2) — chemical structure, CAS 918311-87-2; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyIon ChannelsMonovalent Ion ChannelsSodium Channel Modulators

01 /Applications

Investigation of Slow Afterhyperpolarization (sAHP)

UCL 2077 has been used in research to study the slow afterhyperpolarization (sAHP) phenomenon in specific types of neurons, such as those found in the thalamic paraventricular nucleus (PVT).

Modulation of Neuronal Excitability

This compound has been applied in studies examining its impact on the excitability of hippocampal pyramidal cells, contributing to a deeper understanding of neural circuit function.

Ion Channel Research

As a modulator of ion channels, UCL 2077 serves as a valuable tool for researchers investigating the complex mechanisms of ion transport and signaling within biological systems.

02 /Properties

Molecular weight	350.46
Empirical formula	C25H22N2
Assay	≥98% (HPLC)
Form	solid
Colour	white
Solubility	DMSO: soluble >20 mg/mLH2O: insoluble
Application	UCL 2077 has been used for slow afterhyperpolarization (sAHP) studies in thalamic paraventricular nucleus (PVT) neurons1. UCL 2077 has also been used for studying its effects on the increase in excitability of hippocampal pyramidal cells2.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-36/37/38
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

918311-87-2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is UCL 2077 used for?

UCL 2077 is used in research for studying slow afterhyperpolarization (sAHP) in neurons and its effects on neuronal excitability, particularly in the context of ion channel modulation.

What are the CAS number and formula for UCL 2077?

The CAS number for UCL 2077 is 918311-87-2, and its empirical formula is C25H22N2.

What grade and purity does Tech Serve Solutions supply for UCL 2077?

Tech Serve Solutions supplies UCL 2077 with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.

What are the safety considerations when handling UCL 2077?

UCL 2077 is classified with GHS07 symbol and a 'Warning' signal word. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, faceshields, and gloves, should be used. Handle in a well-ventilated area and avoid breathing dust.