5-Hydroxy-1,4-naphthoquinone
5-Hydroxy-1,4-naphthoquinone (CAS 481-39-0), with the molecular formula C10H6O3 and a molecular weight of 174.15 g/mol, is a crystalline organic compound. It is recognised for its utility as a building block in chemical synthesis, particularly within the realms of organic chemistry and the development of various chemical entities. This compound serves as a valuable intermediate for researchers and industrial chemists.
- IUPAC
- Juglone
- Synonyms
- Juglone5-Hydroxy-1,4-naphthalenedione1,4-Naphthalenedione, 5-hydroxy-

Organic Synthesis Intermediate
5-Hydroxy-1,4-naphthoquinone is employed as a key building block in the synthesis of more complex organic molecules. Its naphthoquinone structure makes it suitable for various chemical transformations, contributing to the development of novel compounds in research and development settings.
Research and Development
This compound finds application in academic and industrial research laboratories. It is utilised in studies exploring new synthetic routes and the creation of diverse chemical structures, supporting advancements in materials science and medicinal chemistry.
Chemical Intermediates
As a carbonyl compound and a ketone, 5-Hydroxy-1,4-naphthoquinone serves as a versatile intermediate. It can be used in reactions that require the specific reactivity of naphthoquinones, facilitating the production of specialised chemicals.
| Molecular weight | 174.15 |
|---|---|
| Empirical formula | C10H6O3 |
| Assay | ≥95.0% (HPLC) |
| Grade | purum |
| Melting point | 161-163 °C(lit.) |


Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality | crystallized |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Hydroxy-1,4-naphthoquinone used for?
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5-Hydroxy-1,4-naphthoquinone is primarily used as a building block and intermediate in organic synthesis and chemical research and development.
What are the CAS number and formula for 5-Hydroxy-1,4-naphthoquinone?
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The CAS number for 5-Hydroxy-1,4-naphthoquinone is 481-39-0, and its molecular formula is C10H6O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Hydroxy-1,4-naphthoquinone with a purity of ≥95.0% (HPLC), in purum grade and crystallized quality. We do not represent this product as USP, BP, or EP grade.
How should 5-Hydroxy-1,4-naphthoquinone be handled safely?
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5-Hydroxy-1,4-naphthoquinone is classified as toxic if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation, and is very toxic to aquatic life. Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a type P2 respirator if necessary. Ensure good ventilation and avoid release to the environment. Refer to the safety data sheet for comprehensive handling instructions.
Is 5-Hydroxy-1,4-naphthoquinone a controlled substance?
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Based on the provided data, there is no indication that 5-Hydroxy-1,4-naphthoquinone is a controlled substance.
How is 5-Hydroxy-1,4-naphthoquinone packed and exported?
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Tech Serve Solutions packs and exports 5-Hydroxy-1,4-naphthoquinone according to relevant chemical shipping regulations. Specific packaging details can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample of 5-Hydroxy-1,4-naphthoquinone, please contact our sales team through the website or by phone, providing your specific requirements.
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