4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers
4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers (CAS 5124-30-1) is a versatile diisocyanate monomer with a molecular weight of 262.35 g/mol. This compound serves as a crucial crosslinking agent in polymer science and materials science. Its reactive isocyanate groups enable the formation of robust polymer networks, finding application in the development of advanced biomaterials and durable coatings.
- IUPAC
- HMDI,Hydrogenated MDI
- Synonyms
- 5124-30-1CH2(C6H10NCO)2HMDIHydrogenated MDI

Polymer Synthesis
Utilised as a diisocyanate monomer, it facilitates the formation of polyurethanes and other polymers through reactions with polyols and other suitable co-monomers. This leads to materials with tailored mechanical and thermal properties.
Crosslinking Agent
Its difunctional nature allows it to act as an effective crosslinking agent, enhancing the strength, durability, and chemical resistance of polymer systems. This is critical in applications requiring high-performance materials.
Biomaterial Development
The compound can be employed in the synthesis of biocompatible polymers for various medical applications. Its ability to form stable urethane linkages is beneficial for creating advanced biomaterials.
Coatings and Adhesives
It contributes to the formulation of high-performance coatings and adhesives, imparting excellent adhesion, flexibility, and resistance to environmental factors due to the formation of a durable polymer matrix.
| Molecular weight | 262.35 |
|---|---|
| Linear formula | CH2(C6H10NCO)2 |
| Assay | 90% |
| Density | 1.066 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.497(lit.) |
| Melting point | 26 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 200 °C / 392 °F |
| Transport (UN / ADR) | UN 2206PSN2B 6.1 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23-36/37/38-42/43 |
| Safety statements (S) | 26-28-38-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers used for?
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This compound is used as a monomer for polymer synthesis, a crosslinking agent in materials science, and in the development of biomaterials, coatings, and adhesives.
What are the CAS number and formula for this product?
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The CAS number is 5124-30-1 and the linear formula is CH2(C6H10NCO)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 90%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should 4,4′-Methylenebis(cyclohexyl isocyanate) be handled safely?
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Due to its hazardous nature (Toxic if inhaled, causes skin and serious eye irritation, may cause respiratory irritation and allergic skin reaction), handle with appropriate personal protective equipment including eyeshields, faceshields, gloves, and a suitable respirator. Ensure adequate ventilation and avoid breathing vapours or dust.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including 4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers.
How can I request a sample or quote?
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Please contact our sales department through the website or by phone to request a sample or a formal quotation for 4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers.
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