PD-166866
PD-166866 (CAS: 192705-79-6) is a bioactive small molecule with the chemical formula C20H24N6O3 and a molecular weight of 396.44 g/mol. This compound serves as a key research tool in cell biology, particularly within cell signalling and neuroscience. It is recognised for its role in investigating kinase/phosphatase biology and receptor tyrosine kinase pathways, making it valuable for drug discovery research and understanding cellular mechanisms.
- IUPAC
- 1-[2-Amino-6-(3,5-dimethoxyphenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butyl urea

Cell Signalling and Neuroscience Research
PD-166866 is utilised as a research chemical to investigate complex cell signalling pathways and their implications in neurological processes. Its role in kinase biology aids in understanding neuronal function and dysfunction.
Receptor Tyrosine Kinase (RTK) Pathway Studies
This compound is valuable for studying RTK signalling, a critical mechanism in cell growth, differentiation, and survival. Researchers use it to probe the roles of specific RTKs in various biological contexts.
Drug Discovery and Development
As a known drug candidate, PD-166866 is employed in preclinical research for the development of novel therapeutics. Its specific biological activity makes it a candidate for investigating potential treatments for various diseases.
Bioactive Small Molecule Investigations
PD-166866 functions as a bioactive small molecule, enabling scientific exploration into cellular responses and molecular interactions. Its defined chemical structure supports precise experimental design.
| Molecular weight | 396.44 |
|---|---|
| Empirical formula | C20H24N6O3 |
| Assay | ≥98% (HPLC) |
| Colour | off-white to light tan |
| Solubility | DMSO: ≥10 mg/mL |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD-166866 used for?
+
PD-166866 is primarily used in research settings for investigating cell signalling, neuroscience, and receptor tyrosine kinase pathways. It also serves as a bioactive small molecule and is recognised as an approved therapeutic/drug candidate for research purposes.
What are the CAS number and formula for PD-166866?
+
The CAS number for PD-166866 is 192705-79-6, and its chemical formula is C20H24N6O3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies PD-166866 with an assay of ≥98% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should PD-166866 be handled and stored?
+
PD-166866 is classified as harmful if swallowed (H302) and requires careful handling. It should be stored at 2-8°C. Always consult the Safety Data Sheet (SDS) before use.
Is PD-166866 available for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including PD-166866, serving researchers and institutions worldwide.
How can I request a quote or sample for PD-166866?
+
To request a quote or sample for PD-166866, please contact our sales team via the website or by telephone. Please specify the quantity required and your shipping details.
▶ Related products

(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology

(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology

(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis