PD-118057
PD-118057 (CAS: 313674-97-4), a dichloro-substituted benzoic acid derivative with the molecular formula C21H17Cl2NO2 and a molecular weight of 386.27 g/mol, is supplied as a light yellow solid. This compound is recognised for its activity in modulating ion channels, particularly voltage-gated potassium channels. Its primary applications are within biochemical research, cell biology, and neuroscience, focusing on cellular signalling pathways and ion channel function.
- IUPAC
- 2-[[4-[2-(3,4-Dichlorophenyl)ethyl]phenyl]amino]benzoic acid
Ion Channel Research
PD-118057 serves as a valuable tool for investigating the function and modulation of ion channels, especially voltage-gated potassium channels. It aids researchers in understanding channel gating mechanisms and the effects of small molecules on cellular excitability.
Cellular Signalling Studies
This compound is utilised to explore cellular signalling pathways influenced by ion channel activity. Its use in research helps elucidate the intricate networks involved in neuronal function and other physiological processes.
Neuroscience Research
PD-118057 finds application in neuroscience research for studying the role of specific ion channels in neural activity. It contributes to the understanding of neurological disorders and the development of potential therapeutic targets.
Biochemical Assays
As a bioactive small molecule, PD-118057 can be employed in various biochemical assays designed to screen for or characterise compounds that interact with potassium channels or related signalling proteins.
| Molecular weight | 386.27 |
|---|---|
| Empirical formula | C21H17Cl2NO2 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | light yellow |
| Solubility | DMSO: soluble9 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | under inert gas |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD-118057 used for?
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PD-118057 is primarily used in biochemical research, cell biology, cell signalling, neuroscience, and ion channel studies, particularly those involving voltage-gated potassium channels.
What are the CAS number and formula for PD-118057?
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The CAS number for PD-118057 is 313674-97-4, and its empirical formula is C21H17Cl2NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PD-118057 with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should PD-118057 be handled safely?
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PD-118057 is classified as a Warning substance (H315-H319-H335-H413). Handle with care using appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes. Work in a well-ventilated area.
How is PD-118057 packaged and shipped?
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PD-118057 is typically supplied as a solid and stored under inert gas at -20°C. For export and shipping, it is packaged according to international regulations for chemical substances.
How can I request a quote or sample for PD-118057?
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To request a quote or sample of PD-118057, please contact the Tech Serve Solutions sales department via our website or direct email, providing your contact details and the quantity required.
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