3-(Chloromethyl)benzoyl chloride
3-(Chloromethyl)benzoyl chloride (CAS 63024-77-1) is a reactive organic compound that functions as a key intermediate in chemical synthesis. Its structure, featuring both a chloromethyl group and an acid chloride, allows for diverse derivatization. This versatile building block is employed in the creation of complex molecules, including specialised polymers and bioactive prodrugs, underscoring its importance in advanced materials and pharmaceutical research.
Polymer Synthesis
Utilised in the preparation of novel amphiphilic star polymers with hyperbranched cores and hydrophilic side chains.
Prodrug Development
Employed in the synthesis of water-soluble and solution-stable bioactive prodrugs for potential therapeutic applications.
Organic Synthesis Intermediate
Serves as a fundamental building block for constructing more complex organic molecules in various research and development settings.
| Molecular weight | 189.04 |
|---|---|
| Linear formula | ClCH2C6H4COCl |
| Assay | 98% |
| Boiling point | 149-150 °C/20 mmHg(lit.) |
| Density | 1.33 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5748(lit.) |
| Application | 3-(Chloromethyl)benzoyl chloride has been used in the preparation of:• new amphiphilic star polymers possessing a hyperbranched core and hydrophilic graft arms1• water-soluble, solution-stable, bioactive prodrugs2 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Chloromethyl)benzoyl chloride used for?
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This compound is primarily used as an intermediate in organic synthesis, particularly in the preparation of amphiphilic star polymers and bioactive prodrugs.
What is the CAS number and formula for 3-(Chloromethyl)benzoyl chloride?
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The CAS number is 63024-77-1, and its linear formula is ClCH₂C₆H₄COCl.
What is the purity or grade of 3-(Chloromethyl)benzoyl chloride?
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This product is supplied at an assay of 98%.
What are the main hazards associated with 3-(Chloromethyl)benzoyl chloride?
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3-(Chloromethyl)benzoyl chloride is classified as Danger, causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, gloves, and suitable respirators, is essential.
How is 3-(Chloromethyl)benzoyl chloride shipped or exported?
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It is classified for transport as UN 3265, Corrosive liquid, acidic, organic, n.o.s. (3-(Chloromethyl)benzoyl chloride), Hazard Class 8, Packing Group II.
How can I request a quote for 3-(Chloromethyl)benzoyl chloride?
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To request a quote, please contact our sales department directly through our website or by phone, providing the product name and CAS number.
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