PD 169316
PD 169316 (CAS 152121-53-4) is a bioactive small molecule with the empirical formula C20H13FN4O2 and a molecular weight of 360.34 g/mol. This compound is a potent inhibitor of p38 mitogen-activated protein kinase (p38MAPK). It is primarily utilized in research settings for its role in cell signalling pathways, particularly within cell biology and neuroscience research. PD 169316 is supplied as a light orange solid.
- IUPAC
- 4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
p38MAPK Inhibition Research
PD 169316 is a selective inhibitor of p38 mitogen-activated protein kinase (p38MAPK). It is used in biochemical and cell-based assays to study the role of p38MAPK signalling in various cellular processes.
Cell Biology Studies
This compound aids in investigating cellular responses to stress, inflammation, and other signalling events regulated by the p38MAPK pathway. Its use is crucial for understanding complex cell biology mechanisms.
Neuroscience Research Tool
As a modulator of cell signalling, PD 169316 is employed in neuroscience research to explore the involvement of p38MAPK in neuronal function and related disorders.
Drug Discovery and Development
PD 169316 serves as a valuable tool in the early stages of drug discovery, particularly for compounds targeting inflammatory and stress-related signalling pathways modulated by p38MAPK.
| Molecular weight | 360.34 |
|---|---|
| Empirical formula | C20H13FN4O2 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | light orange |
| Solubility | DMSO: >10 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... MAPK14(1432) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD 169316 used for?
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PD 169316 is used in research for its potent inhibitory activity against p38 mitogen-activated protein kinase (p38MAPK), aiding studies in cell biology, cell signalling, neuroscience, and drug discovery.
What are the CAS number and formula for PD 169316?
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The CAS number for PD 169316 is 152121-53-4 and its empirical formula is C20H13FN4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PD 169316 with a purity of ≥98% (HPLC). This product is intended for research and development purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should PD 169316 be handled safely?
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PD 169316 is classified as Danger, with hazards including acute toxicity if swallowed (H301), skin irritation (H315), serious eye damage (H318), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is PD 169316 a controlled substance?
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Based on the provided data, PD 169316 is not indicated as a controlled substance.
How is PD 169316 packed and exported?
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PD 169316 is supplied as a solid and stored at 2-8°C. As a global supplier, Tech Serve Solutions is experienced in the compliant packing and export of fine chemicals worldwide, adhering to relevant shipping regulations such as UN 2811 6.1 / PGIII.
How can I request a quote or sample of PD 169316?
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To request a quote or sample of PD 169316, please contact our sales team via the website or direct inquiry. Provide your research needs, and we will assist you with your request.
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