PD 173074
PD 173074 (CAS: 219580-11-7), a potent inhibitor with the molecular formula C28H41N7O3 and a molecular weight of 523.67 g/mol, is primarily used in research. This compound is recognized for its role in cell signalling pathways, particularly those involving fibroblast growth factor receptors (FGFRs). Available as a yellow solid, it serves as a valuable tool for investigating cellular processes and as a potential modulator in stem cell biology research.
- IUPAC
- N-[2-[[4-(Diethylamino)butyl]amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N′-(1,1-dimethylethyl)urea
Fibroblast Growth Factor Receptor (FGFR) Inhibition
PD 173074 is a selective inhibitor of FGFRs, crucial in regulating cell proliferation, differentiation, and survival. Its use is central to studying the role of FGFR signalling in various biological processes and disease states.
Stem Cell Biology Research
This compound serves as an inhibitor in stem cell research, particularly for modulating cell fate and differentiation pathways influenced by FGF signalling. It aids in understanding the mechanisms governing stem cell behaviour.
Cell Signalling Pathway Analysis
PD 173074 is employed to dissect complex cell signalling cascades, especially within neuroscience and cell biology research. It helps researchers understand the intricate interactions of growth factors and their receptors.
| Molecular weight | 523.67 |
|---|---|
| Empirical formula | C28H41N7O3 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | yellow |
| Solubility | DMSO: soluble21 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... FGFR1(2260), KDR(3791)mouse ... Pdgfrb(18596) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD 173074 used for?
+
PD 173074 is used as a research tool, primarily for inhibiting Fibroblast Growth Factor Receptors (FGFRs) and studying cell signalling pathways, including those relevant to stem cell biology and neuroscience.
What are the CAS number and formula for PD 173074?
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The CAS number for PD 173074 is 219580-11-7, and its empirical formula is C28H41N7O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PD 173074 with a purity of ≥98% as determined by HPLC. This product is intended for research purposes and is not supplied as USP, BP, or EP grade.
What are the safety and handling precautions for PD 173074?
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PD 173074 is classified as a Warning (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95, eyeshields, and gloves. Ensure adequate ventilation. Store at 2-8°C.
How is PD 173074 packaged and shipped?
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PD 173074 is typically supplied as a yellow solid and stored at 2-8°C. TSS exports globally, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for PD 173074?
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To request a sample or a quote for PD 173074, please contact our sales team through the website or by phone. We will respond promptly with the information you require.
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