PD 142,893
PD 142,893 (CAS: 155893-16-6) is a synthetic peptide antagonist with the empirical formula C50H65N7O10 and a molecular weight of 924.09 g/mol. This compound is primarily utilised in cell biology research, specifically within cell signaling and neuroscience, and is known for its role in endothelin receptor antagonism. It serves as a valuable tool for investigating cellular pathways and physiological processes.
- IUPAC
- N-Acetyl-β-Phenyl-D-Phe-Leu-Asp-Ile-Ile-Trp
- Synonyms
- C50H65N7O10N-Acetyl-β-Phenyl-D-Phe-Leu-Asp-Ile-Ile-Trp

Endothelin Receptor Antagonism Research
PD 142,893 acts as an antagonist for endothelin receptors, making it a crucial reagent for studying the physiological roles of endothelins in various biological systems. Researchers utilise it to probe signaling pathways modulated by these potent vasoconstrictors.
Cellular Signaling Studies
This peptide is employed to investigate cellular responses and signaling cascades influenced by endothelin receptor activation. Its application aids in understanding complex cell communication mechanisms within neuroscience and other biological contexts.
Neuroscience Research Tool
In neuroscience, PD 142,893 serves as a pharmacological tool to examine the involvement of endothelin receptors in neuronal function and dysfunction. Its specificity allows for targeted investigations into neurological processes.
| Molecular weight | 924.09 |
|---|---|
| Empirical formula | C50H65N7O10 |
| Assay | ≥97% (HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD 142,893 used for?
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PD 142,893 is used as an antagonist in research, particularly for studying endothelin receptors, cellular signaling pathways, and in neuroscience.
What are the CAS number and formula for PD 142,893?
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The CAS number for PD 142,893 is 155893-16-6, and its empirical formula is C50H65N7O10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PD 142,893 with an assay of ≥97% by HPLC. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should PD 142,893 be handled and stored?
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Handle PD 142,893 with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at −20°C.
Is PD 142,893 a controlled substance?
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The provided data does not indicate that PD 142,893 is a controlled substance.
How is PD 142,893 shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including PD 142,893, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for PD 142,893?
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Please contact Tech Serve Solutions directly through our website or designated contact channels to request a sample or a quotation for PD 142,893.
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