PD-161989 2-Hydroxyethanesulfonate
PD-161989 2-Hydroxyethanesulfonate (CAS: 186268-07-5) is a chemical compound with the formula C14H16N4O4 · C2H6O4S and a molecular weight of 430.43 g/mol. It is supplied as a white to off-white powder. This compound is primarily recognised for its role as an AMPA/Kainate antagonist, making it a valuable tool in neuroscience research for studying excitatory amino acid neurotransmission and related cellular processes.
- IUPAC
- 1,4-Dihydro-6-methyl-7-nitro-5-(1-pyrrolodinemethyl)-2,3-quinoxaline 2-hydroxyethanesulfonic acid salt,PD-161989 2-hydroxyethanesulfonic acid salt,PD-161989 isethionate salt
- Synonyms
- 1,4-Dihydro-6-methyl-7-nitro-5-(1-pyrrolodinemethyl)-2,3-quinoxaline 2-hydroxyethanesulfonic acid saltPD-161989 isethionate salt
.png&w=3840&q=75)
Neuroscience Research
PD-161989 2-Hydroxyethanesulfonate serves as a critical pharmacological tool in neuroscience. It is used to investigate the roles of AMPA and kainate receptors in synaptic plasticity, neuronal excitability, and neurological disorders.
Cell Signaling Studies
This compound aids in the study of cell signaling pathways, particularly those involving excitatory amino acid receptors. Its antagonistic properties help researchers elucidate the downstream effects of receptor activation or blockade.
Drug Discovery & Development
As an approved therapeutic candidate, PD-161989 is utilized in preclinical research for potential therapeutic applications. It can be employed in screening assays and mechanism-of-action studies related to neurological conditions.
| Molecular weight | 430.43 |
|---|---|
| Empirical formula | C14H16N4O4 · C2H6O4S |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to off-white |
| Solubility | H2O: ≥10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PD-161989 2-Hydroxyethanesulfonate used for?
+
PD-161989 2-Hydroxyethanesulfonate is used in neuroscience research as an AMPA/Kainate antagonist to study excitatory amino acid neurotransmission, cell signaling, and as a potential therapeutic candidate in drug discovery.
What is the CAS number and chemical formula for PD-161989 2-Hydroxyethanesulfonate?
+
The CAS number for PD-161989 2-Hydroxyethanesulfonate (free base) is 186268-07-5. The chemical formula is C14H16N4O4 · C2H6O4S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies PD-161989 2-Hydroxyethanesulfonate with a purity of ≥98% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should PD-161989 2-Hydroxyethanesulfonate be handled and stored safely?
+
PD-161989 2-Hydroxyethanesulfonate is classified as Danger (GHS06) with hazard statement H301 (Toxic if swallowed). It should be handled with appropriate personal protective equipment in a well-ventilated area. Store at 2-8°C.
How is this chemical typically packed and shipped?
+
This compound is typically supplied as a powder and shipped according to relevant regulations for hazardous materials, indicated by UN 2811, Class 6.1, PGIII.
How can I request a sample or quote for PD-161989 2-Hydroxyethanesulfonate?
+
To request a sample or a quote, please contact our sales department through the website or by phone, providing the product name and CAS number.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis