5-Fluoro-2-methylbenzoyl chloride
5-Fluoro-2-methylbenzoyl chloride (CAS: 21900-39-0) is an organic compound with the molecular formula CH3C6H3(F)COCl and a molecular weight of 172.58 g/mol. This acid halide serves as a valuable intermediate and building block in organic synthesis. It is frequently employed in the preparation of various complex molecules and specialised chemical compounds, contributing to advancements in chemical research and development.

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of more complex organic molecules. Its reactive acyl chloride group facilitates derivatisation for various chemical transformations.
Building Block for Specialty Chemicals
Serves as a foundational building block in the creation of specialty chemicals and fine chemical products. The presence of the fluorine atom and methyl group offers specific electronic and steric properties for targeted syntheses.
Pharmaceutical Intermediate Research
May be employed in research pathways for the development of novel pharmaceutical compounds. Its structure can be incorporated into potential drug candidates undergoing early-stage investigation.
| Molecular weight | 172.58 |
|---|---|
| Linear formula | CH3C6H3(F)COCl |
| Assay | 97% |
| Boiling point | 108 °C/24 mmHg(lit.) |
| Density | 1.270 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.532(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-methylbenzoyl chloride used for?
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5-Fluoro-2-methylbenzoyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly for creating specialty chemicals and in pharmaceutical research.
What is the CAS number and molecular formula?
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The CAS number for 5-Fluoro-2-methylbenzoyl chloride is 21900-39-0, and its molecular formula is CH3C6H3(F)COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-2-methylbenzoyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 5-Fluoro-2-methylbenzoyl chloride be handled?
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5-Fluoro-2-methylbenzoyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including face shields, goggles, gloves, and suitable respiratory protection, is essential. Handle in a well-ventilated area or fume hood.
How is this chemical packed and exported?
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This chemical is packed according to UN 3265, Class 8, Packing Group II standards for safe transportation. Tech Serve Solutions exports fine chemicals globally.
How can I request a quote or sample?
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Please contact our sales team directly via our website or by phone to request a quotation or a sample of 5-Fluoro-2-methylbenzoyl chloride.
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