5-Fluoro-2-methylindole
5-Fluoro-2-methylindole (CAS: 399-72-4) is a fluorinated heterocyclic building block with the molecular formula C9H8FN and a molecular weight of 149.16 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. Its indole core, functionalised with a fluorine atom and a methyl group, offers unique reactivity for complex molecule construction. Sourced from reputable manufacturers, it is available at a purity of 97% for research and development purposes.

Pharmaceutical Synthesis
Used as a key intermediate in the synthesis of drug candidates and active pharmaceutical ingredients (APIs). The fluorinated indole motif is present in various biologically active molecules.
Agrochemical Development
Serves as a building block for the creation of new pesticides, herbicides, and fungicides. Fluorine substitution can often enhance the efficacy and metabolic stability of agrochemical compounds.
Materials Science
Explored for its potential in the development of advanced materials, such as organic electronic components or specialized polymers, where the indole structure can impart desirable properties.
Chemical Research
Employed as a versatile reagent in academic and industrial research laboratories for exploring novel chemical reactions and constructing complex organic frameworks.
| Molecular weight | 149.16 |
|---|---|
| Empirical formula | C9H8FN |
| Assay | 97% |
| Melting point | 98-101 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-methylindole used for?
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5-Fluoro-2-methylindole (CAS: 399-72-4) is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What are the CAS number and molecular formula for 5-Fluoro-2-methylindole?
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The CAS number is 399-72-4, and the molecular formula is C9H8FN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-2-methylindole at an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 5-Fluoro-2-methylindole be handled?
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Handle 5-Fluoro-2-methylindole with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Avoid breathing dust. Ensure adequate ventilation.
Is 5-Fluoro-2-methylindole a controlled substance?
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Based on the provided data, there is no indication that 5-Fluoro-2-methylindole is a controlled substance.
How is 5-Fluoro-2-methylindole packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals in compliance with all relevant international regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a sample or quote for 5-Fluoro-2-methylindole?
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To request a sample or quote for 5-Fluoro-2-methylindole, please contact our sales team through the website or by phone, providing your specific requirements.
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